外泌体是细胞分泌的纳米级囊泡,它们在细胞间通讯中扮演着关键角色,并参与多种生理和病理过程。这些纳米级别的结构不仅能够携带蛋白质、脂质、以及核酸等生物分子,还能穿越生物屏障,如血脑屏障,为靶向药物递送和基因治疗提供了一个全新的平台 ...
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA ...
▎药明康德内容团队编辑  我们知道,人类只有2%的基因真正负责编码蛋白质,而处于非编码区的其余98%一度被视作“垃圾DNA”。但近些年来,这些非编码区域在生命活动中的作用逐渐被揭开。尽管不编码蛋白质,但这些非编码区域也会转录为RNA,其中就包括数千个 ...
Generally, those RNA molecules that do not take the form of mRNA are referred to as noncoding, because they do not encode proteins. The involvement of noncoding mRNAs in many regulatory processes ...
We recommend, however, that you also perform similar intersections with other protein-coding genes, pseudogenes, noncoding genes and gene prediction tracks that appear to be reliable in the region ...
Cancer has a high death rate with delayed diagnosis of the disease being one of the main reasons for its fatality. Early ...
In a recent study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has ...
Researchers use nanowire-based miRNA extraction and machine learning (ML) analysis to detect cancer-associated miRNAs in ...
Cancer cells utilize specific micro-ribonucleic acids (miRNAs)-small noncoding RNAs to regulate gene expression and promote ...