Osteolytic diseases, such as osteoporosis, rheumatoid arthritis, osteosarcoma, and giant-cell tumors of bone, are characterized by increased bone resorption and decreased bone formation, leading to ...
Smoking and air pollution harm bone health. Nicotine reduces bone cell production and calcium absorption. Pollutants cause oxidative stress and inflammation, worsening osteoporosis. Children and ...
Vitamin A contributes to bone growth and the regulation of osteoclasts, the cells responsible for breaking down old bone tissue. However, balance is key, as both deficiency and excess vitamin A ...
In a cross section of this developing mouse fibula bone, the bone-resorbing osteoclasts (purple) organize on the outside of the bone (the periosteum) on the area that's closest to the tibia bone, ...
This Research Topic is part of a series of: https://www.frontiersin.org/research-topics/36924/pharmacological-mechanisms-of-drugs-affecting-bone-formation-and-bone ...