FAO is catalyzed by the mitochondrial trifunctional protein (MTP) and, if overloaded, generates ROS. ROS are boosted during ...

Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more ...

近日，广东省人民医院鲁冰、赵蔚团队在《Nature Cancer》上发表了题为“Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer”的文章。该论文首次揭示了三阴性乳腺癌（TNBC）中存在磷酸化HDAC6蛋白形成的凝聚体，并提出了通过干预磷酸 ...

Herein, we demonstrate a competitive binding of the phospho-Ubl and RING2 domains towards the RING0 domain, which regulates Parkin activity. We show that phosphorylated Parkin can complex with native ...

Application Fluorescent confocal image of HepG2 cells stained with phospho-GATA6-Y271 antibody. HepG2 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.2%, 30 min). Cells were ...

Zhang's team utilized the rapid phospho-shift of OsCTR2, a negative regulator of rice ethylene signaling, in response to ethylene as a sensitive readout for signal activation. Analysis of an ...

Although the role of innate immune sensing pathways is well-studied in the pathogenesis of malignancies, whether they ...

As shown in Figure 2F, spermatogonia that specifically expressing UTF1 were co-stained with the anti-phospho-MLKL antibody. On the other hand, Sertoli cells did not show phospho-MLKL staining even ...