A study reveals that a low-salt fasting-mimicking diet slows kidney disease progression in animal models and shows protective ...

In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease progression. So far, physicians and researchers have found ...

Cells expressing PAX8 (nucleus, red) considered podocyte precursors, line the outer Bowman’s capsule. Activated during the low salt-fasting mimicking diet (LS-FMD), the cells migrate and ...

In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease ...

A specialized low-salt fasting-mimicking diet revives kidney function in preclinical animal models and patients with chronic ...

Purespring’s gene therapy, PS-002, uses a viral vector to target kidney cells—known as podocytes—to treat IgA nephropathy, a ...

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the ...

Cross-sectional images of IgA nephropathy murine kidneys. Purespring gene therapy significantly improves kidney morphology and reduces the areas of scarring and fibrosis stained in blue. Results from ...

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis.

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the ...

This suggests cell type-specific roles of miR-204. We hypothesize that miR-204 in podocytes protects against renal injury, specifically albuminuria via podocyte damage, in hypertension. Methods: We ...