In SNALPs, the backbone-modified siRNA is encapsulated within a closed shell of a cationic-zwitterionic lipid bilayer, furnished with an outer PEG shield (Figure 2A). The lipid bilayer contains a ...

Given their non-migratory nature within the mineralized matrix, their unique dendrites are crucial for cell-to-cell communication in response to both intracellular and extracellular stimuli, such as ...

Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China ...

Methods and Results: We utilized primary CMVECs isolated from inducible endothelial-specific ARNT knockout (KO) mouse hearts and human CMVECs treated with siRNA. ARNT deletion resulted in reduced ...

The Merlin test, also called CP-GEP, combines clinicopathologic variables with gene-expression profiling via qPCR to stratify patients with cutaneous melanoma as high risk or low risk of nodal ...

Ottawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada Department of Biochemistry Microbiology and Immunology, Faculty of Medicine, University of ...