Human and experimental toxicology of diquat poisoning: …
2018年3月23日 — Its toxic potential results from its ability to produce reactive oxygen and nitrogen species through redox cycling processes that can lead to oxidative stress and potentially cell death. Kidney is the main target organ due to DQ toxicokinetics and redox cycling.
High-dose diquat poisoning: a case report - PMC - PubMed …
Diquat has become a widely used herbicide in agriculture since the banning of paraquat in China. The lethal dose of paraquat at a concentration of 20% ranges from 5 to 15 mL. Paraquat has a unique and very unpleasant taste, and most patients spit it out or vomit after oral ingestion.
Mechanisms of toxicity, clinical features, and management of diquat …
Local and systemic effects have been reported following diquat exposure, with systemic features being invariably associated with ingestion. In severe and usually fatal cases, gastrointestinal mucosal ulceration, paralytic ileus, hypovolemic shock, acute renal failure, and …
Human and experimental toxicology of diquat poisoning ... - PubMed
Diquat (1,1'-ethylene-2,2'-bipyridinium ion; DQ) is a nonselective quick-acting herbicide, which is used as contact and preharvest desiccant to control terrestrial and aquatic vegetation. Several cases of human poisoning were reported worldwide …
Diquat Poisoning: Care Management and Medico-Legal Implications
Diquat, a bipyridyl class of herbicides, exerts high intrinsic toxicity as a consequence of free oxygen radicals, leading to cellular death and organ dysfunctions.
Clinical and pathological characteristics of diquat poisoning …
Diquat has replaced paraquat in agricultural areas as a herbicide but has led to extensive poisoning. Unlike paraquat, which targets the lungs, diquat primarily targets the kidneys. Autopsies and animal experiments suggest that interstitial kidney damage is …
Diquat (1,10-ethylene-2,20-bipyridinium ion; DQ) is a nonselective quick-acting herbicide, which is used as contact and preharvest desiccant to control terrestrial and aquatic vegetation. Several cases of human poison-ing were reported worldwide mainly due to intentional ingestion of the liquid formulations.
Diquat Poisoning: Care Management and Medico-Legal …
2022年3月30日 — Diquat, a bipyridyl class of herbicides, exerts high intrinsic toxicity as a consequence of free oxygen radicals, leading to cellular death and organ dysfunctions.
Lethal diquat poisoning manifests as acute central nervous system ...
The mortality rate of acute DQ poisoning was 25 (50%) of 50. Compared with the survival group, the death group presented significantly higher initial plasma DQ concentration (Cp 1), aspartate aminotransferase, alanine aminotransferase, serum creatinine, …
Diquat - Wikipedia
Diquat dibromide is moderately toxic. It may be harmful to humans if swallowed, inhaled, or absorbed through the skin in large quantities. [ 1 ] [ 17 ] Swallowed doses of 10ml and above are often lethal. [ 21 ]
Human and experimental toxicology of diquat poisoning: …
2018年3月23日 — Its toxic potential results from its ability to produce reactive oxygen and nitrogen species through redox cycling processes that can lead to oxidative stress and potentially cell death. Kidney is the main target organ due to DQ toxicokinetics and redox cycling.
Paraquat and Diquat: Recent Updates on Their Pretreatment and …
Paraquat (PQ) and diquat (DQ) are quaternary ammonium herbicides which have been used worldwide for controlling the growth of weeds on land and in water. However, PQ and DQ are well known to be toxic. PQ is especially toxic to humans. Moreover, there is …
Toxicology. When a toxic dose is ingested (see below), paraquat has life-threatening effects on the gastrointestinal tract, kidney, liver, heart and other organs. The LD in humans. 50.
High-dose diquat poisoning: a case report - SAGE Journals
2021年6月29日 — Diquat is a widely used herbicide that is substituted for paraquat. With paraquat off the market, cases of diquat poisoning have been gradually increasing. The kidney is the most frequently impaired organ in diquat poisoning. Few cases of multiple organ failure caused by diquat have been reported.
CASE FILES – Diquat Herbicide - University of Utah Health
2024年5月2日 — Diquat toxicity is most commonly associated with acute kidney injury. Paraquat toxicity is usually more severe and is classically associated with significant lung injury. In severe cases, seizures, coma, and death may occur.
Diquat - an overview | ScienceDirect Topics
Diquat is moderately toxic via oral dosing, with oral LD50 values of 120–233 mg kg −1 in rats, mice, rabbits, guinea pigs, and dogs. Cows are more sensitive, with an oral LD 50 of 30–56 mg kg −1. The acute dermal LD 50 in rabbits is 400–500 mg kg −1.
Diquat Poisoning: Care Management and Medico-Legal Implications
2022年3月30日 — Diquat, a bipyridyl class of herbicides, exerts high intrinsic toxicity as a consequence of free oxygen radicals, leading to cellular death and organ dysfunctions.
Acute diquat poisoning resulting in toxic encephalopathy: a …
2022年1月4日 — Herein, we report three cases of acute diquat poisoning resulting in acute renal failure, neurological disorders, and respiratory failure. This report highlights the imaging features and hypothesis mechanisms of diquat-related toxic encephalopathy.
Imaging Findings and Toxicological Mechanisms of Nervous …
Diquat (DQ) is a nonselective bipyridine herbicide with a structure resembling paraquat (PQ). In recent years, the utilization of DQ as a substitute for PQ has grown, leading to an increase in DQ poisoning cases.
Because diquat is an herbicide, target and non-target plants are especially at risk of negative effects. Data are available indicating that diquat may also be toxic