Ischemia-reperfusion injury: molecular mechanisms and …
2024年1月8日 · Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate...
Reperfusion Injury in Patients With Acute Myocardial Infarction: …
The pathologic and molecular bases for myocardial ischemia-reperfusion injury are increasingly understood and include injury from reactive oxygen species, inflammation, calcium overload, …
Ischemia/Reperfusion Injury: Pathophysiology, Current Clinical ...
Myocardial ischemia reperfusion syndrome is a complex entity where many inflammatory mediators play different roles, both to enhance myocardial infarction-derived damage and to …
Myocardial ischemia/reperfusion injury: Mechanisms of injury …
However, when the interrupted myocardial blood supply is recovered within a certain period of time, it causes more serious damage to the original ischemic myocardium; this is known as …
Fundamentals of Reperfusion Injury for the Clinical Cardiologist
2002年5月21日 · Reperfusion of coronary flow is necessary to resuscitate the ischemic or hypoxic myocardium. Timely reperfusion facilitates cardiomyocyte salvage and decreases cardiac …
Myocardial Ischemia/Reperfusion Injury: Mechanism and …
Myocardial ischemia/reperfusion injury is one of the crucial reasons for morbidity, disability and mortality globally. Understanding the pathological process of cardiomyocyte injury is critical for …
Myocardial Reperfusion Injury | New England Journal of Medicine
2007年9月13日 · Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the …
Myocardial ischaemia–reperfusion injury and cardioprotection in ...
2020年7月3日 · Sustained myocardial ischaemia–reperfusion induces various modes of cardiomyocyte death and coronary microvascular injury. Ischaemic conditioning (cycles of brief …
Reperfusion Injury: How Can We Reduce It by Pre-, Per-, and ...
In ST-elevation myocardial infarction (STEMI), reducing infarct size (IS) is a leading treatment goal to improve clinical outcomes [3]. The most effective way to achieve this is through rapid …
Reperfusion injury of the heart - UpToDate
2023年11月14日 · Myocardial injury in the setting of an acute myocardial infarction (MI) is the result of ischemic and reperfusion injury. Reperfusion therapies, including primary …
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