Treatment of gout flares - UpToDate
2023年11月30日 · The management of gout flares will be reviewed here. The approach to asymptomatic hyperuricemia; the pathophysiology, clinical manifestations, and diagnosis of gout; and the prevention of recurrent gout after resolution of the gout flares are discussed separately: (See "Asymptomatic hyperuricemia".)
Clinical manifestations and diagnosis of gout - UpToDate
2023年5月19日 · Gout (monosodium urate [MSU] crystal deposition disease) is characterized biochemically by extracellular fluid urate saturation, which is reflected in the blood by hyperuricemia, with serum or plasma urate concentrations exceeding 6.8 mg/dL (approximately 400 micromol/L); this level of urate is the approximate limit of urate solubility [1].
Patient education: Gout (Beyond the Basics) - UpToDate
2024年1月18日 · Gout flares (also called gout attacks) are sudden episodes of severe joint pain, usually involving redness, swelling, and tenderness of the joint. Although a gout flare typically affects a single joint, some people develop several inflamed joints at the same time.
Diuretic-induced hyperuricemia and gout - UpToDate
2023年5月30日 · If diuretic-induced gout occurs, it is typically treated with a urate-lowering drug such as allopurinol. The pathogenesis, epidemiology, and an overview of treatment of diuretic-induced hyperuricemia and gout are presented in this topic.
COPD exacerbations: Management - UpToDate
2024年7月12日 · The management of patients with exacerbations of COPD is discussed here. A table to assist with emergency management of severe acute exacerbations of COPD is provided ( table 1 ). The diagnosis and treatment of infection in exacerbations and the management of stable COPD are discussed separately.
Treatment of acute decompensated heart failure: Specific therapies
2024年8月1日 · The components of therapy of ADHF in patients without acute myocardial infarction (MI) will be reviewed here. A table to assist with emergency management of ADHF is provided (table 1). General considerations for treatment of ADHF and the pathophysiology and evaluation of patients with ADHF are presented separately.
Diuretic-induced hyperuricemia and gout - UpToDate
2021年11月17日 · The pathogenesis, epidemiology, and an overview of treatment of diuretic-induced hyperuricemia and gout are presented in this topic. The pathophysiology, clinical manifestations, diagnosis, and treatment of gout flares as well as the prevention of gout flares are discussed separately:
Clinical manifestations and diagnosis of systemic lupus …
2023年6月16日 · The various cutaneous manifestations of SLE are presented in detail separately. (See "Overview of cutaneous lupus erythematosus".) Many patients develop oral and/or nasal ulcers, which are usually painless in contrast to herpetic chancre blisters. Nasal ulcers may lead to nasal septal perforation.
Pharmacologic urate-lowering therapy and treatment of tophi
2024年6月11日 · Management for the prevention of recurrent gout flares and damage to joints and other tissues from urate crystal deposition includes drug therapy, lifestyle modifications, and other strategies for risk reduction.
Overview of the treatment of myasthenia gravis - UpToDate
2024年9月6日 · This topic will discuss the overall treatment of generalized MG. Detailed reviews of chronic immunotherapies for MG and thymectomy for MG are found separately. (See "Chronic immunotherapy for myasthenia gravis" and "Role of thymectomy in patients with …