Atherogenesis - an overview | ScienceDirect Topics
Atherogenesis is a chronic inflammatory disorder characterized by endothelial dysfunction and the accumulation of a number of cellular components within the vascular intima • Atherogenesis is enhanced by a number of risk factors, including hypercholesterolaemia, smoking, diabetes mellitus, hypertension and family history •
Atherogenesis: current understanding of the causes of atheroma
The purpose of this review is to summarise current understanding of the pathogenesis and progression of atherosclerosis with particular reference to potential new diagnostic or therapeutic approaches.
Atherosclerosis - Mechanisms of Vascular Disease - NCBI Bookshelf
Atherogenesis involves intercommunication between shared pathways involved in adaptive and innate immunity. Various established and emerging risk factors for atherosclerosis modulate aspects of immune responses, including lipoproteins and their modified products, HSPs, and infectious agents.
The changing landscape of atherosclerosis | Nature
2021年4月21日 · This Review addresses the evolving concepts of atherogenesis and the opportunities for preventing and treating atherosclerosis afforded by new insights into its pathogenesis.
Pathophysiology of Coronary Artery Disease | Circulation
2005年6月28日 · Previously considered a cholesterol storage disease, we currently understand atherogenesis as a complex interaction of risk factors including cells of the artery wall and the blood and molecular messages that they exchange.
Current Understanding of Atherogenesis - PubMed
Scientific understanding of atherogenesis is constantly developing. From Virchow's observations 160 years ago we now recognize the endothelial response to injury as inflammatory, involved in all stages of atherosclerosis.
Atherogenesis - an overview | ScienceDirect Topics
Atherogenesis refers to the process of developing plaques within blood vessel walls due to interactions involving blood elements, vessel wall abnormalities, and changes in blood flow.
How the immune system shapes atherosclerosis: roles of innate …
2021年8月13日 · Atherosclerosis, which is a common pathology underlying many cardiovascular diseases, is characterized by the accumulation of lipid-laden, immune cell-rich plaques known as atheromata in large and...
Atherosclerosis: Pathogenesis and Key Cellular Processes
Atherosclerosis is the principal cause of cardiovascular disease that continues to be a substantial drain on healthcare systems, being responsible for about 31% of all global deaths. Atherogenesis is influenced by a range of factors, including oxidative stress, inflammation, hypertension, and hyperlipidemia, and is ultimately driven by the ...
Atherogenesis: current understanding of the causes of atheroma
The pathogenesis of atherosclerosis (first of two parts). N Engl J Med. 1976 Aug 12;295(7):369–377. [ PubMed] [ Google Scholar] Shanahan CM, Weissberg PL. Smooth muscle cell heterogeneity: patterns of gene expression in vascular smooth muscle cells in …
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