Puromycin: Uses, Interactions, Mechanism of Action - DrugBank
Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
The science of puromycin: From studies of ribosome function to ... - PubMed
2020年4月24日 — Puromycin is a naturally occurring aminonucleoside antibiotic that inhibits protein synthesis by ribosome-catalyzed incorporation into the C-terminus of elongating nascent chains, blocking further extension and resulting in premature termination of translation.
The science of puromycin: From studies of ribosome function to ...
2020年2月22日 — Puromycin is a naturally occurring aminonucleoside antibiotic that inhibits protein synthesis by ribosome-catalyzed incorporation into the C-terminus of elongating nascent chains, blocking further extension and resulting in premature termination of translation.
Puromycin is a naturally occurring aminonucleoside antibiotic that inhibits protein synthesis by ribosome-catalyzed incorporation into the C-terminus of elongating nascent chains, blocking further extension and resulting in premature termination of translation.
Puromycin - an overview | ScienceDirect Topics
Puromycin is a naturally occurring aminonucleoside antibiotic that inhibits protein synthesis by ribosome-catalyzed incorporation into the C-terminus of elongating nascent chains, blocking further extension and resulting in premature termination of translation.
Puromycin | C22H29N7O5 | CID 439530 - PubChem
Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.
Puromycin - an overview | ScienceDirect Topics
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It is a very common antibiotic routinely used by scientists in biomedical research to select cells modified by genetic engineering. It specifically inhibits peptidyl transfer on …
Puromycin - SpringerLink
Puromycin1, an antibiotic isolated from culture filtrates of Streptomyces alboniger (Porter et al., 1952), is well-characterized chemically and biologically. Its structure, shown in Fig. 1, has been established both by degradative studies and total...
Cell-type-specific quantification of protein synthesis in vivo
2019年1月4日 — The synthesis of O -propargyl-puromycin (OP-Puro), an analog of puromycin that contains a terminal alkyne group, has facilitated the quantification of protein synthesis within individual...
Puromycin reactivity does not accurately localize ... - eLife
2020年8月26日 — Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes. Puromycin has been used in molecular biology research for decades as a translation inhibitor.
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