Acetylcholinesterase - Wikipedia
Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters:
Physiology, Acetylcholinesterase - StatPearls - NCBI Bookshelf
2023年1月19日 · Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally …
Acetylcholinesterase: From 3D Structure to Function - PMC
By rapid hydrolysis of the neurotransmitter, acetylcholine, acetylcholinesterase terminates neurotransmission at cholinergic synapses. Acetylcholinesterase is a very fast enzyme, functioning at a rate approaching that of a diffusion-controlled reaction.
Acetylcholinesterase - an overview | ScienceDirect Topics
Acetylcholinesterase (AChE) is a serine protease degrades acetylcholine between cholinergic synapses and terminates cholinergic neural signaling (Silman and Sussman 2008). Studies have revealed that AChE activity was reduced in PD patients with cognitive impairment, and the loss of cholinergic was observed within the central and peripheral ...
Acetylcholinesterase - SpringerLink
2018年1月1日 · Acetylcholinesterase is a serine hydrolase that cleaves choline esters rapidly, preferentially acetylcholine (ACh). AChE shows a great ACh-hydrolyzing capacity, and in the list of enzymes classified according to their catalytic efficiency AChE occupies the second position.
Acetylcholinesterase Inhibitors: Pharmacology and ... - PMC
Hence, acetylcholinesterase inhibitors, interacting with the enzyme as their primary target, are applied as relevant drugs and toxins. This review presents an overview of toxicology and pharmacology of reversible and irreversible acetylcholinesterase inactivating compounds.
Molecule of the Month: Acetylcholinesterase - RCSB: PDB-101
Acetylcholinesterase is found in the synapse between nerve cells and muscle cells. It waits patiently and springs into action soon after a signal is passed, breaking down the acetylcholine into its two component parts, acetic acid and choline.
Physiology, Acetylcholine - StatPearls - NCBI Bookshelf
2023年4月10日 · Free acetylcholine within the synaptic cleft is degraded by an enzyme called acetylcholinesterase. This enzyme assures that no excess of acetylcholine remains in the synaptic cleft to cause the continuous activation of receptors.
Physiology, Acetylcholinesterase - PubMed
2023年1月19日 · Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally …
Cholinesterase - Wikipedia
Acetylcholinesterase (EC 3.1.1.7) (ACHE), also known as AChE, choline esterase I, RBC cholinesterase, or erythrocyte cholinesterase, true cholinesterase, choline esterase I, or (most formally) acetylcholine acetylhydrolase, is found primarily in the blood on red blood cell membranes, in neuromuscular junctions, and in other neural synapses ...
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