β-Lactam antibiotic - Wikipedia
β-Lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a β-lactam ring in their chemical structure. This includes penicillin derivatives ( penams ), cephalosporins and cephamycins ( cephems ), monobactams , carbapenems [ 1 ] and carbacephems . [ 2 ]
Beta-Lactam Antibiotics - StatPearls - NCBI Bookshelf
2023年6月4日 · Beta-lactam antibiotics are used in the management and treatment of bacterial infections. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of an interprofessional ...
β-内酰胺类抗生素 - 百度百科
β-内酰胺类抗生素（Beta-lactam antibiotic）是一种种类很广的抗生素，其中包括 青霉素 及其衍生物、 头孢菌素 、单酰胺环类、 碳青霉烯类 和青霉烯类酶抑制剂等。. β-内酰胺类抗生素（β-lactams）系指化学结构中具有β-内酰胺环的一大类抗生素，基本上所有在其 ...
Β-内酰胺抗生素 - 维基百科，自由的百科全书
β-內醯胺抗生素 （β-lactam antibiotics）是化学结构中具有 β-内酰胺环 的一大类 抗生素，包括 青霉素 及其衍生物、 頭孢菌素 、 单酰胺环类 （英语：monobactam） 、 碳青霉烯 和青霉烯类酶抑制剂等。. 基本上所有在其分子结构中包括 β-内酰胺 核的抗生素均属于β ...
Beta-lactam antibiotics: Mechanisms of action and resistance …
2023年11月15日 · Beta-lactam antibiotics are among the most commonly prescribed drugs, grouped together based upon a shared structural feature, the beta-lactam ring. Beta-lactam antibiotics include: Penicillins Cephalosporins Cephamycins Carbapenems
Overview of Beta-Lactams - Overview of Beta-Lactams - The …
Beta-lactamases are a diverse class of enzymes produced by bacteria that break open the beta-lactam ring, inactivating the beta-lactam antibiotic. Some beta-lactamases are encoded on mobile genetic elements (eg, plasmids); others are encoded on chromosomes. Beta-lactamase production is among the most clinically important mechanisms of ...
Structural Insights for β-Lactam Antibiotics - PMC
2023年3月3日 · To date, various β-lactam antibiotics have been developed to increase the spectrum of activity and evade drug resistance. This review emphasizes the three-dimensional structural characteristics of β-lactam antibiotics regarding the overall scaffold, working mechanism, chemical diversity, and hydrolysis mechanism by β-lactamases.
β-lactam antibiotics: An overview from a medicinal chemistry ...
2020年12月15日 · β-Lactam antibiotics are one of the most relevant drug classes of antibacterial agents worldwide. The discovery and the market of first β-lactam antibiotic (Penicillin G) is a symbolic landmark of modern chemotherapy. Since then, several other β-lactam antibiotics have been introduced in the therapy, revolutionizing the treatment of ...
β-lactam antibiotics: An overview from a medicinal chemistry ...
2020年12月15日 · The β-lactam antibiotics is a family of bactericidal drugs structurally-related containing the β-lactam ring in their chemical structure. They are classified in penicillins, cephalosporins, carbapenems, penems (also known as thiopenems) and monobactams.
Beta-Lactam Antibiotics - PubMed
2023年6月4日 · Beta-lactam antibiotics are used in the management and treatment of bacterial infections. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent ….