Guanethidine - Wikipedia
Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. Guanethidine is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself (NET, uptake 1), and uptake is essential for the drug's action.
胍乙啶 - 百度百科
该品作抗高血压药用其硫酸盐，有两种硫酸盐：胍乙啶硫酸盐，C10H22N4·0.5H2SO4，[60-02-6]，Guanethidine sulfate，溶点276-281℃（分解）。 胍乙啶一硫酸盐，C10H22N4·H2SO4，[645-43-2]，Guanethidine monosulfate.
Guanethidine: Uses, Interactions, Mechanism of Action
2005年6月13日 · Guanethidine is an antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension.
Guanethidine (oral route) - Mayo Clinic
2024年2月1日 · Guanethidine belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension). High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, …
胍乙啶：吲哚类生物碱降压药 - 知乎 - 知乎专栏
胍乙啶是一种抗高血压药物，属于肾上腺素能神经元阻断药，能够干扰交感神经末梢释放去甲肾上腺素，从而降低心排血量和末梢血管阻力，导致血压下降。. 胍乙啶的研发始于1950年代，当时美国的一位医学博士生约翰·奥特曼（John Oates）在研究去甲肾上腺素的 ...
呱乙啶 - 百度百科
分子式：C10H22N4. 药理 ：口服后起效较慢，3～4天降压作用始达高峰，作用强大而持久。. 降压时伴心率减慢，心输出量减少与脉压减小。. 大剂量静脉注射，开始排出较多的去甲肾上腺素并阻止囊泡再吸收，致血压上升。. 慢性给药开始因递质不能释放而降压 ...
Guanethidine | C10H22N4 | CID 3518 - PubChem
Guanethidine works by decreasing the heart rate and relaxing the blood vessels so that blood can flow more easily through the body, thereby reducing these risks. It is a postganglionic sympathetic nerve terminal blocker that prevents the release of norepinephrine from nerve terminals.
藥理學/抗高血壓/抑制交感神經功能/Guanethidine - 维基教科 …
延遲射精或是逆行射精（即精液逆行涉入膀胱）. 對於有 嗜鉻細胞瘤的病人，服用此藥，會因為兒茶酚胺釋放， 導致高血壓危象 （103-2-23）. 對於有在服用三環抗憂鬱者，併用此藥，會因為抗高血壓效果被抑制，可能會有嚴重高血壓. 此页面最后编辑于2019年2月14 ...
Guanethidine - an overview | ScienceDirect Topics
Guanethidine reduces noradrenaline (norepinephrine) concentrations in adrenergic neurons and blocks reuptake. The technique of intravenous regional guanethidine block (IVRGB) described by Hannington-Kiff (1974) quickly became established as a simple and reliable method of peripheral sympathetic blockade and is now widely used.
GUANETHIDINE ( GUANETHIDINE SULFATE )的適應症、成分、 …
GUANETHIDINE ( GUANETHIDINE SULFATE )的適應症、成分、用法與用量、作用機轉、副作用. 中度及嚴重高血壓。. 一般的每日劑量25∼50mg。. 促使神經末梢無法儲存並順利釋出正腎上腺素，進而減低心臟血液輸出量並使末梢血管放鬆，使血壓下降，可治療高血壓。. 促使 ...