Interleukin 10 - Wikipedia
IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory …
Interleukin 10 - an overview | ScienceDirect Topics
Interleukin 10 (IL-10) is an anti-inflammatory cytokine that is a member of the class-2 cytokines. In humans, interleukin 10 is encoded by the IL10 gene (loc: 1q32.1) and is produced primarily by …
Role of Interleukin 10 Transcriptional Regulation in Inflammation …
Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that plays a central role in limiting host immune response to pathogens, thereby preventing damage to the host and …
Biology and therapeutic potential of interleukin-10 - PMC
Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL …
Interleukin - StatPearls - NCBI Bookshelf - National Center for ...
2022年8月22日 · Interleukin-9 (IL-9) Th9, Th2, Th17, mast cells, NKT cells, and regulatory T cells produce this cytokine. It enhances T-cell survival, mast cell activation and synergy with …
Interleukin-10: new perspectives on an old cytokine - PMC
Interleukin-10 (IL-10) has long been recognized to have potent and broad-spectrum anti-inflammatory activity, which has been unequivocally established in various models of infection, …
The regulation of IL-10 production by immune cells - Nature
2010年2月15日 · Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central role in infection by limiting the immune response to pathogens and thereby preventing damage …
Frontiers | The multifaceted nature of IL-10: regulation, role in ...
2023年5月24日 · Circulating interleukin 10 (IL-10) binds as a homodimer to tetrameric IL-10 receptor (IL-10R) complex and induce the downstream activation of Janus kinase 1 (Jak1) and …
Interleukin-10: biology, role in inflammation and autoimmunity
Interleukin-10 is an important molecule with a central role in maintaining health and in the pathogenesis of disease. Known pharmacologic agents and some under investigation can …
IL-10: The Master Regulator of Immunity to Infection
2008年5月1日 · Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated …