Interleukin 17 - Wikipedia
Interleukin 17 family (IL17 family) is a family of pro-inflammatory cystine knot cytokines. [2] They are produced by a group of T helper cell known as T helper 17 cell in response to their …
大热靶点IL-17丨百家争鸣 力争上游 - 知乎 - 知乎专栏
2022年5月7日 · 白细胞介素17 (interleukin 17, IL17)是由CD4+ T细胞分泌，能够诱导上皮细胞、内皮细胞、成纤维细胞合成分泌IL-6、IL-8、G-CSF、PGE2，促进ICAM-1的表达的促炎因子。.
Basic biology and role of interleukin-17 in immunity and inflammation
Interleukin-17 (IL-17, also known as IL-17A) is a key cytokine that links T cell activation to neutrophil mobilization and activation. As such, IL-17 can mediate protective innate immunity …
The IL-17 family in diseases: from bench to bedside | Signal
2023年10月11日 · Interleukin 17 (IL-17) is an important cytokine that has several roles in host defense responses against mucosal infections; additionally, it is a primary pathologic cytokine …
Interleukin-17 and its target genes: mechanisms of interleukin-17 ...
Interleukin-17 (IL-17) has emerged as a central player in the mammalian immune system. Although this cytokine exerts a host-defensive role in many infectious diseases, it promotes …
Interleukin-17 in human inflammatory diseases - PMC
IL-17A in humans are associated with pathology in numerous autoimmune and inflammatory conditions, such as rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, Crohn's …
Interleukin 17 is a chief orchestrator of immunity - Nature
2017年5月18日 · Increased understanding of the biology of interleukin 17 (IL-17) has revealed that this cytokine is a central player in immunity at the sites most exposed to microorganisms.
Biology of Interleukin-17 and Its Pathophysiological ... - PubMed
2020年7月28日 · Several recent studies have indicated that IL-17A is a biomarker as well as a therapeutic target in sepsis. In the current review, we summarize the biological functions of IL …
Interleukin-17 and its expanding biological functions
2010年4月12日 · IL-17 and IL-17-producing cells exert various functions in host defense and pathological conditions. Here, we will summarize the biological characteristics of IL-17 and its …
The IL-17 Family of Cytokines in Health and Disease
2019年4月16日 · The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A through IL-17F. IL-17A, the prototypical member of this family, just passed …