The apoptosis/autophagy paradox: autophagic vacuolization …
2005年7月15日 · Serum and amino acid-starved LAMP2-negative cells exhibited an accumulation of autophagic vacuoles and then succumbed to cell death with hallmarks of apoptosis such as …
Cytoplasmic vacuolation, adaptation and cell death: A view on …
1999年9月1日 · Vacuoles reported in apoptotic cells tend to be either lipidfilled or autophagic vacuoles, quite unlike those induced by, eg procaine. We have examined DNA fragmentation …
Morphologic and biochemical hallmarks of apoptosis
2000年2月1日 · Apoptosis is characterised by a series of typical morphological features, such as shrinkage of the cell, fragmentation into membrane-bound apoptotic bodies and rapid …
Apoptotic cell fragments locally activate tingible body …
2023年3月2日 · Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with …
Apoptosis: A Review of Programmed Cell Death - PMC - PubMed …
Apoptotic cells exhibit several biochemical modifications such as protein cleavage, protein cross-linking, ... large clear vacuoles; and (6) blebs at the cell surface. As apoptosis progresses, …
Apoptotic cells in mouse blastocysts are eliminated by ... - Nature
2021年4月29日 · Apoptosis is a physiological process that occurs commonly during the development of the preimplantation embryo. The present work examines the ability of …
Vacuolar functions determine the mode of cell death
2009年3月1日 · Our findings suggest a role of the vacuole/lysosomes in a switch from necrotic to apoptotic death phenotype, giving it control over all responses to acetic stress and making it …
Apoptotic Bodies: Mechanism of Formation, Isolation and …
2021年3月30日 · Apoptotic bodies (ApoBDs), a major subset of ApoEVs, are formed through a process termed apoptotic cell disassembly characterised by a series of tightly regulated …
When apoptosis meets autophagy: deciding cell fate after trauma …
Apoptosis is a type I PCD and is morphologically characterized by chromatin condensation, nuclear fragmentation, cell surface blebbing, cell shrinkage and formation of apoptotic bodies. …
Apoptosis | Arteriosclerosis, Thrombosis, and Vascular Biology
1999年1月1日 · Apoptosis, in contrast, is a programmed, active, highly selective mechanism of cell death allowing for the removal of cells that are redundant or excessively damaged. 1 …