Binding immunoglobulin protein - Wikipedia
BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains them in …
The endoplasmic reticulum (ER) chaperone BiP is a master …
The ER heat shock protein 70 (Hsp70) family member BiP is an ATP-dependent chaperone that plays a critical role in these processes. BiP interacts with specific ER-localized DnaJ family …
UPR proteins IRE1 and PERK switch BiP from chaperone to ER ... - Nature
2019年11月6日 · BiP is a major endoplasmic reticulum (ER) chaperone and is suggested to act as primary sensor in the activation of the unfolded protein response (UPR). How BiP operates as …
Endoplasmic reticulum chaperone BiP/GRP78 knockdown …
2020年11月12日 · The immunoglobulin heavy chain binding protein (BiP), also referred to as 78-kDa glucose-regulated protein (GRP78), is a pivotal endoplasmic reticulum (ER) chaperone …
The endoplasmic reticulum protein HSPA5/BiP is essential for …
2024年10月29日 · Protein expression of BiP, IRE1a and PERK was evaluated by Western Blot analysis as previously reported 20. Briefly, EnSCs cultured in 12-well plates were lysed with …
Binding Immunoglobulin Protein - an overview - ScienceDirect
BiP (Immunoglobulin Binding Protein) BiP is a 78-kDa ER chaperone that binds immunoglobulins. It is a monomeric protein with two distinct functional domains, an ATP-binding domain and a …
BiP: Master Regulator of the Unfolded Protein Response and …
2017年6月23日 · Binding immunoglobulin protein (BiP) acts as a master regulator for the process, and thus plays a key role in the UPR. Viruses, as obligate intracellular pathogens, rely heavily …
BINDING PROTEIN Is a Master Regulator of the Endoplasmic …
2013年4月24日 · BINDING PROTEIN (BiP) is a major chaperone in the endoplasmic reticulum (ER) lumen, and this study shows that BiP binds to the C-terminal tail of the stress …
The endoplasmic reticulum–residing chaperone BiP is short
2018年1月2日 · Here, we show that BiP was a short-lived protein. BiP is Nt-arginylated in response to ER stress and proteasomal inhibition as part of protein quality control, leading to …
Role and regulation of the ER chaperone BiP - PubMed
BiP, an HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER), binds newly-synthesized proteins as they are translocated into the ER and maintains them in a …