Brotizolam - Wikipedia
Brotizolam is prescribed for the short-term treatment, 2–4 weeks only of severe or debilitating insomnia. Insomnia can be described as a difficulty falling asleep, frequent awakening, early awakenings or a combination of each.
Brotizolam: Uses, Interactions, Mechanism of Action - DrugBank …
2014年6月23日 · Brotizolam is a benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia.
Brotizolam | C15H10BrClN4S | CID 2451 - PubChem
Brotizolam is a triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS).
Brotizolam. A review of its pharmacodynamic and …
Brotizolam is a new thienotriazolodiazepine derivative with a pharmacological profile similar to that of benzodiazepines. It is indicated for use as an hypnotic in the management of insomnia, although it also has anticonvulsant, antianxiety and muscle relaxant properties in animals.
Brotizolam - an overview | ScienceDirect Topics
Brotizolam is a triazolothienodiazepine used in the treatment of insomnia and also has anticonvulsant, antianxiety and muscle relaxant properties. It reduces latency to sleep, reduces the number of awakenings and waking time during sleep, and increases total sleep time [1].
BROTIZOLAM - National Center for Advancing Translational …
Brotizolam (marketed under brand name Lendormin) is a sedative-hypnotic thienotriazolodiazepine drug which is a benzodiazepine analog. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to short-acting benzodiazepines such as triazolam.
Brotizolam: Uses, Dosage, Side Effects, FAQ - MedicinesFAQ
2023年9月19日 · Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. Brotizolam is an extremely potent drug and it is rapidly eliminated with an average half-life of 4.4 hours (range 3.6 - 7.9 hours).
Brotizolam | Drugs - Springer
2012年10月23日 · Brotizolam is a new thienotriazolodiazepine derivative with a pharmacological profile similar to that of benzodiazepines. it is indicated for use as an hypnotic in the management of insomnia, although it also has anticonvulsant, antianxiety and …
Brotizolam - PMC - National Center for Biotechnology Information
All doses increased total sleep time, improved the sleep efficiency index, and reduced drowsy sleep and number of awakenings. Brotizolam (0.4 and 0.6 mg) also reduced awake activity. There was some evidence of a delay to the first REM period, but only 0.6 mg reduced the total duration of REM sleep. There were no changes in slow wave sleep.
Brotizolam - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf
2024年1月15日 · Very little information is available on the passage of brotizolam into milk, although amounts in milk appear to be very low. An alternate drug might be preferred, especially while nursing a newborn or preterm infant. If brotizolam is used, monitor the infant for sedation, poor feeding and poor weight gain.
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