Deamination - Wikipedia
Deamination is the removal of an amino group from a molecule. [1] Enzymes that catalyse this reaction are called deaminases. In the human body, deamination takes place primarily in the liver; however, it can also occur in the kidney.
6.4: Protein Metabolism - Medicine LibreTexts
Deamination is the removal of the amine group as ammonia (\(\ce{NH3}\)), as shown below. Figure \(\PageIndex{2}\): Deamination of cytosine to uracil (nucleotides, not amino acids) 2 The potential problem with deamination is that too much ammonia is toxic, causing a condition known as hyperammonemia.
Deamination - an overview | ScienceDirect Topics
Deamination involves the loss of amino groups from DNA bases. Almost all DNA bases undergo deamination in spontaneous reactions, with the exception of thymine – which does not have an amino group.
29.9 Catabolism of Proteins: Deamination - OpenStax
Deamination is usually accomplished by a transamination reaction in which the –NH 2 group of the amino acid is exchanged with the keto group of α-ketoglutarate, forming a new α-keto acid plus glutamate.
Deamination - Explanation, Types and Differences - Vedantu
The process of removing an amino group from a molecule is called deamination, when the amino group is changed into ammonia. The enzyme that stimulates this action is called deaminases. Deamination principally occurs in the liver; however, glutamate is also deaminated in the kidney.
29.9: Catabolism of Proteins- Deamination - Chemistry LibreTexts
2024年9月23日 · Deamination is usually accomplished by a transamination reaction in which the –NH 2 group of the amino acid is exchanged with the keto group of α-ketoglutarate, forming a new α-keto acid plus glutamate.
5.9: Amino Acid Degradation - Biology LibreTexts
2022年12月30日 · In their conversion to metabolic intermediates, the amino acids first undergo deamination. The primary goal of deamination is to excrete excess nitrogen (as urea) and then use or convert (to glucose) the remaining carbon skeleton.
Deamination - SpringerLink
Definition. Deamination describes the loss of an amine group from a molecule. Overview. Deamination is likely to have played an important role in the availability of the biological building blocks of life.
The Curious Chemical Biology of Cytosine: Deamination, Methylation …
Deamination of cytosine contributes to genetic variability by promoting purposeful mutations, as evidenced in the maturation of immune responses. Cytosine methylation or oxidation refines the genome by tailoring a gene program to a given cell lineage or altering gene expression in the face of environmental changes.
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
2022年3月7日 · Introduction. Genetic information is encoded by DNA, transcribed into RNA and translated into protein. When originally proposed 1, this foundational tenet assumed faithful transmission of...
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