Dexamethasone for Nausea and Vomiting - ChemoExperts
Dexamethasone is designed to help prevent both early and delayed nausea and vomiting caused by chemotherapy. Goals of dexamethasone (Decadron®) therapy: Dexamethasone is commonly given on a scheduled basis to prevent nausea and vomiting.
Dexamethasone to prevent postoperative nausea and vomiting: …
2012年12月12日 · Background: Dexamethasone has an established role in decreasing postoperative nausea and vomiting (PONV); however, the optimal dexamethasone dose for reducing PONV when it is used as a single or combination prophylactic strategy has …
The cellular mechanisms of the antiemetic action of dexamethasone …
2014年1月5日 · Dexamethasone, one of the glucocorticoids, has been suggested as a first-line drug for preventing low-level emetogenic chemotherapy- and radiotherapy-induced nausea and vomiting, and in patients with only one or two risks for …
Benefits and Risks of Dexamethasone in Noncardiac Surgery
We recommend dexamethasone (4 to 8 mg) for the prophylaxis and treatment of postoperative nausea and vomiting; the higher dose provides an antiemetic benefit for up to 72 h. 22 A dose of 8 mg IV dexamethasone provides some analgesic benefit, particularly in orthopedic, oral, and ear, nose, and throat surgeries, and otherwise improves patient ...
Antiemetics: ASCO Guideline Update | Journal of Clinical Oncology
2020年7月13日 · Dexamethasone is a potent corticosteroid that is a critical component of a number of antiemetic guideline–endorsed regimens for use in the prevention of nausea and vomiting caused by chemotherapy.
Antiemetic drugs: what to prescribe and when - PMC
Serotonin and neurokinin antagonists, such as ondansetron and aprepitant, are highly effective in treating chemotherapy-induced nausea and vomiting. Metoclopramide and antihistamines are first-line options for nausea and vomiting in pregnancy.
Dexamethasone to prevent postoperative nausea and vomiting: …
A single dose of 4mg to 5mg dexamethasone was statistically significantly more effective than control at reducing the incidence of 24-hour nausea and/or vomiting (OR 0.31, 95% CI 0.24 to 0.42; NNT=3.7; 14 RCTs).
Prevention of chemotherapy-induced nausea and vomiting in adults
2024年8月14日 · Three distinct types of CINV have been defined, with important implications for both prevention and management: Acute emesis, which most commonly begins within one to two hours of chemotherapy and usually peaks in four to six hours. Delayed emesis, occurring more than 24 hours after chemotherapy.
Prevention and Treatment of Postoperative Nausea and …
A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy.
Dexamethasone to Prevent Postoperative Nausea and Vomiting - LWW
Dexamethasone has an established role in decreasing postoperative nausea and vomiting (PONV); however, the optimal dexamethasone dose for reducing PONV when it is used as a single or combination prophylactic strategy has not been clearly defined.