A Guide to Dendritic Cell Markers - Biocompare
2021年3月4日 · In this article, we will review the major dendritic cell subpopulations and their associated protein markers. Markers for dendritic cell precursors. In the classical model of dendritic cell (DC) development, hematopoietic stem cells in the bone marrow give rise to macrophage and DC precursors (MDPs).
The Dendritic Cell Lineage: Ontogeny and Function of ...
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, ...
Human dendritic cell subsets: an update - PMC
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid haematopoiesis that form an essential interface between the innate sensing of pathogens and the activation of adaptive immunity.
Human dendritic cell subsets - PMC - PubMed Central (PMC)
Dendritic cell production from human progenitors is promoted by Flt-3 ligand, GM-CSF and IL-4 in vitro 35 and Flt-3, macrophage colony-stimulating factor (M-CSF) and GM-CSF signalling via signal transducers and activators of transcription 3 and 5 is likely to play an important role in vivo.
Dendritic cell migration in inflammation and immunity - Nature
2021年7月23日 · Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and play crucial roles in both the promotion of immune defense and the maintenance of immune tolerance.
Dendritic Cell Overview | Thermo Fisher Scientific - US
Dendritic cells (DCs) develop from hematopoietic stem cells (HSCs) in a multistep process that begins in the bone marrow. Most DCs arise through a common DC progenitor (CDP) that differentiates into conventional DC precursors (pre-cDCs) and plasmacytoid DC precursors (pre-pDCs) in a fms-like tyrosine kinase 3 (FLT3) ligand-dependent manner.
Dendritic Cells & their Markers - Bio-Rad
Classical and plasmacytoid dendritic cell function, ontogeny and phenotype overviews, including key CD marker identification. Along with antibodies to these mononuclear phagocytes of the innate immune system.