EDNRA Gene - GeneCards | EDNRA Protein | EDNRA Antibody
2024年10月1日 · EDNRA (Endothelin Receptor Type A) is a Protein Coding gene. Diseases associated with EDNRA include Mandibulofacial Dysostosis With Alopecia and Migraine With Or Without Aura 1. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling.
EDNRA protein expression summary - The Human Protein Atlas
A summary of the overall protein expression profile across the analyzed normal tissues based on knowledge-based annotation, presented in the Tissue resource. "Estimation of protein expression could not be performed. View primary data."
EDNRA endothelin receptor type A [ (human)] - National Center …
Ednra, encoding Endothelin receptor A (ETA)-the target of Endothelin 1 (ET-1)-was significantly increased in Systemic Capillary Leak Syndrome blood-outgrowth endothelial cells compared to healthy controls.
Endothelin 1-induced retinal ganglion cell death is largely
2020年9月26日 · Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells (RGCs), the output neurons of the retina. Multiple lines of evidence show the endothelin (EDN, also known...
Vascular derived endothelin receptor A controls endothelin …
2022年4月16日 · The endothelin system is a family of three ligands (EDN1, 2, and 3, also known as ET-1, 2, and 3) and two G-protein coupled receptors (EDNRA and EDNRB, also known as ET-A and ET-B). The canonical...
EDNRA endothelin receptor type A [ Homo sapiens (human) ]
2024年11月2日 · Summary. This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system.
Current and future strategies for targeting the endothelin pathway …
2023年11月2日 · GWAS have suggested EDNRA gene (which encodes the ET A receptor) variants are relevant to risk of aneurysmal SAH in Japanese people 37. This is particularly pertinent when considering the higher...
High Endothelin Receptor Type A Expression as an Independent …
2021年6月28日 · EDNRA, binding to EDN1, is part of the G protein-coupled receptors and can regulate relevant signal pathways. The EDN1/EDNRA axis plays a major role in cellular processes, such as cell growth, differentiation, invasiveness, and tumor progression in …
High Endothelin Receptor Type A Expression as an Independent
2021年6月28日 · Endothelin receptor type A (EDNRA) is associated with guanine-nucleotide-binding (G) proteins and plays important roles in cellular processes and various diseases. Purpose: To investigate the prognosis value of EDNRA expression and its correlation with immune infiltrates in patients with STAD.
Endothelins (EDN1, EDN2, EDN3) and their receptors (EDNRA, …
2019年11月1日 · In mammals, only two EDN receptors (EDNRA and EDNRB) and three EDNs have been identified. Both EDNRA and EDNRB are likely coupled to Gq and Gs/Gi protein and their activation triggers multiple signaling pathways similar but not identical to those in chickens.
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