FCGR3B Gene - GeneCards | FCG3B Protein | FCG3B Antibody
Oct 2, 2024 · FCGR3B (Fc Gamma Receptor IIIb) is a Protein Coding gene. Diseases associated with FCGR3B include Neutropenia, Severe Congenital, X-Linked and Neonatal Alloimmune Neutropenia. Among its related pathways are Innate Immune System and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include IgG binding.
中性粒细胞 单细胞测序：中性粒细胞 marker（一） - 知乎
Mar 20, 2024 · 中性粒细胞marker：FCGR3B, CSF3R 2. High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in nonsmall cell lung cancer | Cancer cell (IF=50.3)
iScience丨单细胞转录组鉴定出FCGR3B 在重症新冠患者中上调
Nov 24, 2021 · 最近，Mohammed Uddin 的团队及合作者在《Cell》的子刊《iScience》发表了一篇标题为“Single-cell transcriptome identifies FCGR3B upregulated subtype of alveolar macrophagesin patients with critical COVID-19” 的研究论文，该研究表明，FCGR3B可能在重症新冠肺炎患者中识别出一种特殊的MoAM亚型，这可能为筛查和预后提供一个新的生物标志物，以及一个潜在的治疗靶点。 单细胞转录组学和细胞类型鉴定. 为了鉴定与重症COVID-19相关的细 …
FCGR3B - Wikipedia
FCGR3B (Fc fragment of IgG, low affinity IIIb, receptor), also known as CD16b (C luster of D ifferentiation 16b), is a human gene. [5] Mutations and copy-number variations in this gene have been associated to clinical cases of glomerulonephritis. [6] ^ "Human PubMed Reference:".
FCGR3B Fc gamma receptor IIIb [ Homo sapiens (human) ]
Nov 2, 2024 · Low copy number of the Fc-γ receptor 3B gene FCGR3B is a risk factor for primary Sjogren's syndrome. Nossent JC, et al. J Rheumatol, 2012 Nov. PMID 22942264. FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans. Molokhia M, et al. Rheumatology (Oxford), 2011 Jul. PMID 21296850, Free PMC Article.
FCGR3B Fc gamma receptor IIIb [ (human)] - National Center for ...
Apr 11, 2024 · Results showed that susceptibility to systemic lupus erythematosus was associated with the FCGR3B*01 allele, as well as with the FCGR3B*01/*01 and FCGR3B*01/*02 genotypes. FcgammaRIIIB allelic distribution was similar among pediatric Guillain-Barre syndrome patients and controls.
Single-cell transcriptome identifies FCGR3B upregulated subtype …
FCGR3B consistently demarcated MoAM subset in different samples from severe COVID-19 cohorts and in CCL3L1 -upregulated cells from nasopharyngeal swabs. In silico findings were validated by upregulation of FCGR3B in nasopharyngeal swabs of severe ICU COVID-19 cases, particularly in older patients and those with comorbidities.
FCGR3B - an overview | ScienceDirect Topics
The FCGR3 family is made up of FCGR3A and FCGR3B, which are located adjacent to each other on chromosome 1q23. FCGR3B is highly homologous to FCGR3A, which encodes FcγRIIIa (Table 10-5). The most important difference between the two genes is a C to T change at position 733nt in FCGR3B that creates a stop codon.
O75015 - UniProt
There are three allelic forms of FCGR3B: FCGR3B*01 (HNA-1a, NA-1), FCGR3B*02 (HNA-1b, NA-2) and FCGR3B*03 (HNA-1c, SH). FCGR3B*01 and FCGR3B*02 are detectable with antibodies against the biallelic neutrophil-specific antigen system NA.
Fcγ receptors: structure, function and role as genetic risk …
May 7, 2009 · Two genes, FCGR3A and FCGR3B, encode the two receptors of the FcγRIII family (FcγRIIIa and FcγRIIIb). FcγRIII is also considered as of low affinity; however, FcγRIIIA can bind monomeric IgG ...