HL60 - Wikipedia
The HL-60 cell line is a human leukemia cell line that has been used for laboratory research on blood cell formation and physiology. HL-60 proliferates continuously in suspension culture in nutrient and antibiotic chemicals. The doubling time is about 36–48 hours.
HL-60 - CCL-240 - ATCC
HL-60 cells are promyeoloblasts isolated from the peripheral blood by leukopheresis from a 36-year-old,White, female with acute promyelocytic leukemia. This cell line can be used in immune disorder and immunology research. Product category. Human cells. Organism. Homo sapiens, human. Cell type. promyeloblast. Morphology. Lymphoblast-like. Tissue.
The HL60 cell line: a model system for studying human myeloid …
The HL60 cell line was established in 1977 from a patient with acute myeloid leukaemia. The cells largely resemble promyelocytes but can be induced to differentiate terminally in vitro. Some reagents cause HL60 cells to differentiate to granulocyte-like cells, others to monocyte/macrophage-like cell ….
Chemotaxis and swarming in differentiated HL-60 neutrophil-like …
2021年1月12日 · The human leukemia cell line (HL-60) is an alternative to primary neutrophils in research studies. However, because HL-60 cells proliferate in an incompletely differentiated state, they...
Molecular Characterization of Human Leukemia 60 (HL-60) …
The use of human leukemic (HL)-60 cells is important for studies of acute myeloid leukemia (AML) and as a model system for investigating how specific types of blood cells are formed during the process of hematopoiesis. Here, we present a protocol for growth of HL-60 cells along with molecular and fu …
An Effective Model of the Retinoic Acid Induced HL-60 ... - Nature
2017年10月30日 · We constructed an effective model of ATRA-induced HL-60 differentiation which described signaling and gene expression events following the addition of ATRA (Fig. 1). HL-60 is a NCI-60 cell...
HL-60 Cell Line - an overview | ScienceDirect Topics
The HL-60 cell line is a promyelocytic cell line derived from human leukemia (Collins, Gallo, & Gallagher, 1977). The cells are premyelocytes, but can be induced in vitro to differentiate into different lineages of mature myeloid cells depending on the reagents used for induction (Collins, Ruscetti, Gallagher, & Gallo, 1978).
Cellosaurus cell line HL-60 (CVCL_0002)
Comparison of the complete mtDNA genome sequences of human cell lines-- HL-60 and GM10742A -- from individuals with pro-myelocytic leukemia and Leber hereditary optic neuropathy, respectively, and the inclusion of HL-60 in the NIST human mitochondrial DNA standard reference material -- SRM 2392-I.
HL60 - an overview | ScienceDirect Topics
HL60 is a human caucasian promyelocytic leukemia cell line (Figure 7.3 (a)), derived from a 36-year-old woman with acute PML at the National Cancer Institute. HL60 cells are predominantly a neutrophilic promyelocyte, used for laboratory research on how certain kinds of …
HL-60 Cell Line - an overview | ScienceDirect Topics
The human leukemia cell line (HL-60) is a promyelocytic cell line. In the 1977, it was derived from a 36-year-old Caucasian woman who suffered from acute myeloid leukemia (Birnie, 1988). This cell line has been extensively used for studying diverse topics including leukemia, therapeutics, and myeloid differentiation (Basu et al., 2023).