HaCaT - Wikipedia
HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, [1] [2] widely used in scientific research. [3] HaCaT cells are utilized for their high capacity to differentiate and proliferate in vitro. [4]
Cellosaurus cell line HaCaT (CVCL_0038)
The human keratinocyte cell line HaCaT: an in vitro cell culture model for keratinocyte testosterone metabolism. Pharm. Res. 16:766-771(1999) PubMed= 10523843 ; DOI= 10.1038/sj.onc.1202934
Growth and differentiation of HaCaT keratinocytes - PubMed
HaCaT cells are a spontaneously immortalized, human keratinocyte line that has been widely used for studies of skin biology and differentiation. Under typical culture conditions HaCaT cells have a partially to fully differentiated phenotype due …
Growth and Differentiation of HaCaT Keratinocytes
2013年10月24日 · HaCaT cells are a spontaneously immortalized, human keratinocyte line that has been widely used for studies of skin biology and differentiation. Under typical culture conditions HaCaT cells have a partially to fully differentiated phenotype due to the high calcium...
HaCaT cells as a model system to study primary cilia in keratinocytes
Spontaneously immortalized human keratinocytes, HaCaT are a model to study the epidermal homeostasis and pathophysiology. In contrast to what has been previously described, here, we show that HaCaT can be efficiently ciliated.
Immortalized N/TERT keratinocytes as an alternative cell
2017年9月19日 · The HaCaT cell line, a spontaneously immortalized human keratinocyte cell line, is widely used in keratinocyte monolayer culture models and also described for the development of organotypic skin...
HaCaT - an overview | ScienceDirect Topics
HaCaT cells are a human epidermal keratinocyte line that has been used for investigation of multistep carcinogenesis in human cells (Boukamp et al. 1988). HaCaTs retain epidermal keratins characteristic of the more differentiated cell layers of human epidermis in vivo and are useful for in vivo analysis ( Breitkreutz et al. 1991 ).
HaCaT Cell Line - Exploring Skin Biology and Disease - Cytion
HaCaT cells are a spontaneously immortalized human keratinocyte cell line originating from adult skin and representing a unique evolutionary pathway. These cells possess mutations in both alleles of the p53 gene, which is typical for mutations induced by UV radiation [3,4].
HaCaT Keratinocytes and Primary Epidermal Keratinocytes Have …
HaCaT cells are the immortalized human keratinocytes and have been extensively used to study the epidermal homeostasis and its pathophysiology. T helper cells play a role in various chronic dermatological conditions and they can affect skin barrier homeostasis.
Experiments were performed with the HaCat cell lines, the first permanent epithelial cell line for human skin, similar to normal keratinocytes, that exibits normal differentation and provides a resistant and promising tool to study keratinization reaction in human cells (16).