KINK-1, a Novel Small-Molecule Inhibitor of IKKβ, and the ...
2008年6月18日 · KINK-1 strongly suppressed both constitutive and induced NF-κB activity in melanoma cells. It reduced the expression of NF-κB–dependent gene products that regulate …
KINK-1, a novel small-molecule inhibitor of IKKbeta, and the ...
2008年6月18日 · The antitumoral efficacy of KINK-1 in combination with the cytostatic agents doxorubicin or camptothecin (all injected intraperitoneally) was tested in vivo by measuring …
KINK-1 = 98 HPLC 600734-06-3 - MilliporeSigma
KINK-1 (Kinase Inhibitor of NF-ΚB-1; Bay 65-1942; CmpdA; Compound A) is an ATP-competitive, IKKβ-selective IΚB kinase (IKK) inhibitor (Ki against ATP = 2 nM/IKKβ and 135 nM/IKKα) that …
KINK-1, a novel small-molecule inhibitor of IKKbeta, and the ...
2008年6月18日 · KINK-1 strongly suppressed both constitutive and induced NF-kappaB activity in melanoma cells and markedly increased the activities of some cytostatic agents in vitro and …
KINK-1, a Novel Small-Molecule Inhibitor of IKK , and the ...
2008年6月1日 · The effects of KINK-1 (alone and in combination with cytostatic agents) on melanoma cells were characterized by assessing proliferation, soft agar colony formation, and …
KINK-1, a novel small-molecule inhibitor of IKKbeta, and the ...
2008年6月12日 · KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment. by Margarete Schön, B Gregor Wienrich, Susanne …
KINK-1, a novel small-molecule inhibitor of IKKbeta, and the ...
2008年6月10日 · KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment. 1 Europe PMC requires Javascript to function …
KINK-1, a novel small-molecule inhibitor of IKKbeta, and the ...
KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment. Journal of the National Cancer Institute ( IF 10.3) Pub Date : 2008 Jun …
KINK-1 = 98 HPLC 600734-06-3 - MilliporeSigma
KINK-1 hydrochloride (Bay 65-1942 ); >= 98% HPLC; Orally active, potent, ATP-competitive, IKKβ (IKK2)-selective inhibitor with anti-inflammatory and anti-cancer efficacy in vivo; KINK-1 …
GEO Accession viewer - National Center for Biotechnology …
2019年3月25日 · We have identified KINK-1 (Kinase Inhibitor of NF-kappaB-1), a highly selective small-molecule IKKkappa inhibitor, as a potent suppressor of both constitutive and induced NF …
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