Lysophospholipid - an overview | ScienceDirect Topics
A lysophospholipid is defined as a molecule with only one hydrocarbon chain, exhibiting properties similar to detergents such as being amphipathic and forming micelles. AI generated definition based on: The Membranes of Cells (Third Edition), 2016
甘油磷脂的代谢及相关生理功能 - 知乎 - 知乎专栏
磷脂被PLA1或PLA2水解除去一分子脂肪酸后生成的产物称为溶血磷脂（lysophospholipid，LP），因为它含有一个疏水烃链和一个极性磷酸基团，是强去污剂，可破坏细胞膜，使红细胞破裂而发生溶血。
Emerging roles of lysophospholipids in health and disease
2020年11月1日 · Revealing how circulating lysophospholipids are produced, released, transported, and utilized in multi-organ systems is critical to understand their functions. The discovery of enzymes, carriers, transporters, and membrane receptors for these lysophospholipids has shed light on their physiological significance.
Lysophospholipids - SpringerLink
Lysophospholipids are small bioactive lipid molecules characterized by a single carbon chain and a polar head group. Two subgroups can be distinguished: molecules containing the sphingoid base backbone (lysosphingolipids) and molecules containing the glycerol backbone (lysoglycerophospholipids).
Role of lysophosphatidic acid and its receptors in health and …
2021年2月1日 · Lysophosphatidic acid (LPA) is an abundant bioactive phospholipid, with multiple functions both in development and in pathological conditions. Here, we review the literature about the differential...
Differential activation mechanisms of lipid GPCRs by ... - Nature
2022年2月8日 · Lysophospholipids are bioactive lipids and can signal through G-protein-coupled receptors (GPCRs). The best studied lysophospholipids are lysophosphatidic acid (LPA) and sphingosine 1-phosphate...
Lysophospholipids - SpringerLink
2022年1月1日 · Lysophospholipids are small bioactive lipid molecules characterized by a single carbon chain and a phosphate-containing polar head group. Two subgroups can be distinguished: molecules based on the glycerol backbone (lysoglycerophospholipids) and molecules based on the sphingoid base backbone (lysosphingolipids).
Lysophospholipids: Advances in Synthesis and Biological Significance ...
2015年1月1日 · A lysophospholipid (LP) is a phospholipid that is missing one of its two O-acyl chains (free hydroxyl group in either the sn-1 or sn-2 position). Lysophospholipids are good emulsifying and solubilizing agents as well as synthons for many synthetic phospholipids used in food, cosmetics, agrochemicals, and pharmaceuticals ( Aoi, 1990 ; Dennis et ...
Lysophospholipid Mediators in Health and Disease - PMC
2022年1月1日 · Lysophospholipids, exemplified by lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), are produced by the metabolism and perturbation of biological membranes. Both molecules are established extracellular lipid mediators that signal via specific G protein–coupled receptors in vertebrates.
Structural insights into the lysophospholipid brain uptake …
2022年6月16日 · Brain development and function require uptake of essential omega-3 fatty acids in the form of lysophosphatidylcholine via major-facilitator superfamily transporter MFSD2A, a potential...