The Ovarian Stroma as a New Frontier - PMC - National Center …
网页The ratio of ovarian stromal area to total ovarian area (S/A) by ultrasound was a good predictor of hyperandrogenism in lean Italian women with PCOS, with increased ovarian vascularization and blood flow noted in PCOS patients as compared to controls (Battaglia et al., 2012), and S/A ratio has been proposed as a method to refine the Rotterdam ...
The ovarian stroma as a new frontier - PubMed
网页Historically, research in ovarian biology has focused on folliculogenesis, but recently the ovarian stroma has become an exciting new frontier for research, holding critical keys to understanding complex ovarian dynamics. Ovarian follicles, which are the functional units of the ovary, comprise the o ….
Stroma of ovary - Wikipedia
网页The stroma of the ovary is a unique type of connective tissue abundantly supplied with blood vessels, consisting for the most part of spindle-shaped stroma cells. These appear similar to fibroblasts. The stroma also contains ordinary connective tissue such as reticular fibers and collagen.
The ovarian stroma as a new frontier
网页Historically, research in ovarian biology has focused on folliculogenesis, but recently the ovarian stroma has become an exciting new frontier for research, holding critical keys to understanding complex ovarian dynamics.
The stromal microenvironment and ovarian aging: mechanisms …
网页2023年12月13日 · In this review, we summarize the role of stromal components in ovarian aging, describing their age-related alterations and associated effects. Moreover, we list some potential techniques that may mitigate ovarian aging based on their effect on the stromal microenvironment.
The stromal microenvironment and ovarian aging: mechanisms …
网页Ovarian microenvironment plays a significant role in mediating somatic aging and follicular part. Orthotopic transplantation of ovarian tissue between young and aged mice demonstrated that a healthy stromal microenvironment plays an essential role in folliculogenesis [22].
Human theca arises from ovarian stroma and is comprised of …
网页2023年1月4日 · Theca cells serve multiple essential functions during the growth and maturation of ovarian follicles, providing structural, metabolic, and steroidogenic support.
The stromal microenvironment and ovarian aging: mechanisms …
网页2023年12月13日 · Abstract. For decades, most studies of ovarian aging have focused on its functional units, known as follicles, which include oocytes and granulosa cells. However, in the ovarian stroma, there are a variety of somatic components that bridge the gap between general aging and ovarian senescence.
NADase CD38 is a key determinant of ovarian aging - Nature
网页2023年12月21日 · In situ immunostaining identified that CD38 protein mainly localized in ovarian stroma. The ovarian stroma not only offers structural support for follicle development but also engages in...
Anatomy, Development, Histology and Normal Function of the Ovary …
网页The body of the ovary (ovarian stroma) consists of specialized spindle-shaped cells and a smaller amount of ordinary connective tissue. The core of the ovarian stroma (the medulla; M) contains the ovary’s main vessels, whereas the peripheral zone (the cortex; C) contains follicles (F) at various stages of development.