RNA interference - Wikipedia
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression.
RNA Interference (RNAi) - National Center for Biotechnology Information
2017年11月9日 · RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is a conserved biological response to double-stranded RNA that mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What is RNAi - RNAi Biology | UMass Chan Medical School
The term RNA interference (RNAi) was coined to describe a cellular mechanism that uses the gene's own DNA sequence to turn it off, a process that researchers call silencing. In a wide variety of organisms, including animals, plants, and fungi, RNAi is …
RNA interference | Explanation, Function, & Examples - Britannica
2024年10月18日 · RNA interference (RNAi), regulatory system occurring within eukaryotic cells (cells with a clearly defined nucleus) that controls the activity of genes. RNAi functions specifically to silence, or deactivate, genes.
RNA Interference: Biology, Mechanism, and Applications - PMC
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.
RNA interference in the era of nucleic acid therapeutics
2024年2月26日 · Two decades of research on RNA interference (RNAi) have transformed a breakthrough discovery in biology into a robust platform for a new class of medicines that modulate mRNA expression.
The current state and future directions of RNAi-based therapeutics
2019年3月7日 · The RNA interference (RNAi) pathway regulates mRNA stability and translation in nearly all human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of specific...
RNA interference: biology, mechanism, and applications
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.
RNA interference - Nature
2002年7月11日 · A conserved biological response to double-stranded RNA, known variously as RNA interference (RNAi) or post-transcriptional gene silencing, mediates resistance to both endogenous parasitic and...
Molecular mechanisms of RNA interference - PMC - PubMed …
The discovery of RNA interference (RNAi) revolutionized our understanding of gene regulation by revealing an array of related pathways in which small ~20–30 nucleotide (nt) non-coding RNAs and their associated proteins control the expression of genetic information .