Human RNase P: overview of a ribonuclease of interrelated …
The seminal discovery of ribonuclease P (RNase P) and its catalytic RNA by Sidney Altman has not only revolutionized our understanding of life, but also opened new fields for scientific …
Ribonuclease P: The Evolution of an Ancient RNA Enzyme
Ribonuclease P (RNase P) is an ancient and essential endonuclease that catalyses the cleavage of the 5′ leader sequence from precursor tRNAs (pre-tRNAs). The enzyme is one of only two …
RNase P - an overview | ScienceDirect Topics
RNase P is an endo-ribonuclease required for processing precursor tRNA into mature tRNA. RNase P is a highly conserved ribonucleoprotein composed of (i) an RNA ribozyme that …
Bacterial RNase P: a new view of an ancient enzyme
2006年10月1日 · Ribonuclease P (RNase P) is a ubiquitous endonuclease that catalyses the maturation of the 5′ end of transfer RNA (tRNA).
Ribonuclease P - PMC
Ribonuclease P (RNase P) is an endoribonuclease that cleaves other RNA molecules at the junction between a single-stranded region and the 5′ end of a double-stranded region. In …
RNase P: Variations and Uses - Journal of Biological Chemistry
RNase P is responsible for generating the mature 5′-end of tRNAs by a single endonucleolytic cleavage of their precursors. It is an essential, ubiquitous enzyme present in all cells and …
RNase P enzymes - PMC - National Center for Biotechnology …
2013年6月1日 · Ribonuclease P (RNase P) catalyzes the maturation of the 5′ end of precursor-tRNAs (pre-tRNA) and is conserved in all domains of life. However, the composition of RNase …
Structural basis of RNA processing by human mitochondrial RNase P …
2021年9月6日 · The cryo-EM structure of human mitochondrial RNase P bound to precursor tRNA reveals the molecular basis for the first step of RNA processing in human mitochondria.
Human RNase P: a tRNA-processing enzyme and transcription factor
2007年5月5日 · NUCLEAR RNase P: AN ENSEMBLE OF RNA WITH HIGHLY CONSERVED PROTEINS. Ribonuclease P (RNase P) was originally described as an endoribonuclease that …
Both kinds of RNase P in all domains of life: surprises galore
2018年8月9日 · An example of such convergent evolution is presented by RNase P, a housekeeping endonuclease that functions primarily in 5′-maturation of tRNAs in all domains …
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