Sirolimus - Wikipedia
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
What is rapamycin? - New Scientist
Originally developed as an immunosuppressant for organ transplant patients, it has found a new lease on life as a potential anti-ageing drug. Rapamycin has not been approved for that use in...
The Risky Anti-Aging Pill Men Are Taking Now - Rapamycin
2019年7月19日 · The FDA stamped rapamycin with a “black box” warning, its most extreme, for drugs that come with “serious or life-threatening risks”—risks like infections, pneumonia, and cancer.
Rapamycin may slow aging. Here's one way the drug will be …
2024年7月1日 · Now a dentist is testing if rapamycin stops gum disease — a canary in the coal mine for age-related diseases.
Rapamycin: Anti-Aging Benefits and Possible Side Effects
2024年7月18日 · However, thus far, the promise of using rapamycin as a supplement has been offset by side effects associated with high doses. This article will explore how rapamycin works, its benefits, mechanisms, and potential for treating diseases and prolonging a healthy life.
Is Rapamycin the Key to a Longer, Healthier Life? Here’s What …
2024年11月4日 · Exploring Rapamycin’s Potential in Aging Rapamycin’s role in transplant medicine has provided invaluable insights into its effects on the body. These findings set the stage for a new frontier in research, where scientists are investigating whether rapamycin’s carefully calibrated, short-term use could tap into the same longevity pathways ...
Targeting the biology of aging with mTOR inhibitors - Nature
2023年5月4日 · Treatment of aged mice with rapamycin restored the functional capacity of their HSCs and boosted the immune response to influenza virus. In a separate study, rapamycin was shown to restore self...
What You Should Know About Rapamycin and If It Can Really …
2024年8月29日 · Rapamycin has been called a potential miracle drug, capable of slowing the effects of aging — everything from greying hair to age-related diseases like Alzheimer’s. And even though the bacteria that produces rapamycin was discovered about six decades ago, the drug still isn’t used or prescribed often. In the early phases of testing ...
Targeting ageing with rapamycin and its derivatives in ...
Rapamycin and its derivatives (rapalogs) are inhibitors of mTOR, a major regulator of the ageing process. We aimed to summarise the effects of rapamycin and its derivatives on the severity of ageing-related physiological changes and disease in adults. A search across five databases yielded 18 400 unique articles, resulting in 19 included ...
Rapamycin golden jubilee and still the miraculous drug: a potent ...
Although celebrating its golden jubilee, rapamycin’s importance keeps increasing by the day. Starting as a promising antifungal agent, then as a potent immunosuppressant, strong anticancer drug, and now rapamycin is attracting serious attention as a ...