Alkannin - Wikipedia
Alkannin is a natural dye that is obtained from the extracts of the plant dyer's alkanet (Alkanna tinctoria) which is found in the Mediterranean region. The dye is used as a food coloring and in cosmetics; within the European E number schedule, it is numbered E103.
Frontiers | Review of Shikonin and Derivatives: Isolation, Chemistry ...
2022年6月30日 · Shikonin’s anti-cancer activity against HeLa cells can be increased by combining melatonin with shikonin (Li et al., 2020). Shikonin and its derivatives were effective against leukaemia cell lines, U937 (cell line model) (Zhao et al., 2015).
Shikonin in breast cancer treatment: a comprehensive review of ...
2024年4月23日 · Shikonin, a chemical homologous to estrogen, develops its anticancer effects in a dose-dependent manner by inhibiting ERα and/or related signaling pathways in luminal BRCA cells. Shikonin inhibits estrogen-stimulated cell proliferation in luminal BRCA cells without affecting normal human mammary epithelial cells.
Pharmacological Effects of Shikonin and Its Potential in Skin
2023年12月5日 · Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese medicine Shikonin, has favorable biological activities such as anti-inflammatory, antibacterial, immunomodulatory, anticancer, and wound …
Frontiers | The anti-leukemia activity and mechanisms of shikonin: …
2023年11月1日 · Shikonin (SHK) is a naphthoquinone derivative that shows multiple biological function includes anti-tumor, anti-inflammatory, and anti-allergic effects. Numerous studies have reported the anti-leukemia activity of SHK during the last 3 decades and there are studies showing that SHK is particularly effective towards various leukemia cells ...
Effect and mechanisms of shikonin on breast cancer cells in vitro …
6 天之前 · Shikonin inhibits the growth of 4T1 breast cancer cells by disrupting mitochondrial activity, promoting oxidative stress, and regulating immune function. Breast cancer seriously affects physical and mental health of women. Despite advances in the clinical use of different treatments, breast cancer remains a major cause of mortality.
Lithospermum erythrorhizon. Shikonin is one of the active principles of Zicao, the root extract of Lithospermum erythrorhizon Sieb. et Zucc. (Boraginaceae), widely used in traditional Chinese medicine for its anti-inflammatory properties [1].
Pharmacological Significance of Boraginaceae with Special Insights …
2024年4月27日 · Shikonin is a naphthoquinone pigment present in the hairy roots of the plant species from the Boraginaceae family. The compound has been well investigated for its highly efficient medicinal, antioxidant, and antimicrobial properties.
shikonin successfully prevented geographic damage, hyperfluorescence, regional hypofluorescence, and the increased vascular permeability caused by DM/hypoxia-induced retinopathy.
Shikonin - SpringerLink
2018年11月20日 · Shikonin is a naphthoquinone isolated from Arnebia species such as Arnebia euchroma. The dried root of A.euchroma is a traditional Chinese medicine with anti-inflammatory and antiviral activities.