Tamsulosin - Wikipedia
Tamsulosin, sold under the brand name Flomax among others, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones.
Tamsulosin: Uses, Interactions, Mechanism of Action - DrugBank …
Mechanism of action. Tamsulosin is a blocker of alpha-1A and alpha-1D adrenoceptors. Label,1 About 70% of the alpha-1 adrenoceptors in the prostate are of the alpha-1A subtype. Label By blocking these adrenoceptors, smooth muscle in the prostate is …
Tamsulosin: a review of its pharmacology and therapeutic ... - PubMed
Tamsulosin has a rapid onset of action and is effective in patients with moderate or severe symptoms. The drug is therefore a valuable therapeutic option, with both demonstrated and potential advantages over older nonselective agents, in the management of patients with LUTS associated with BPH.
Tamsulosin: Dosage, Mechanism/Onset of Action, Half-Life
Mechanism of Action. Tamsulosin is an antagonist of alpha 1A-adrenoreceptors in the prostate. Smooth muscle tone in the prostate is mediated by alpha 1A-adrenoreceptors; blocking them leads to relaxation of smooth muscle in the bladder neck and prostate causing an improvement of urine flow and decreased symptoms of BPH
Alpha-Blockers - StatPearls - NCBI Bookshelf
2023年7月3日 · Identify the mechanism of action and administration of alpha-blockers. Describe the adverse effects and contraindications of alpha-blockers. Outline the appropriate monitoring and management for the toxicity of alpha-blockers.
Tamsulosin oral controlled absorption system (OCAS) in the …
The efficacy of tamsulosin at the cost of a relatively benign side effect profile has been attributed to receptor selectivity directed at the α1a and α1d adrenergic receptor subtypes. The oral-controlled absorption system (OCAS®) represents a drug ...
Tamsulosin - an overview | ScienceDirect Topics
Tamsulosin is a competitive alpha-1 adrenoceptor antagonist with some selectivity for alpha-1A and alpha-1D relative to alpha-1B adrenoceptor subtypes. It is used clinically for the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
Tamsulosin in urology: beyond benign prostatic hyperplasia
2019年2月19日 · Mechanism of action. Tamsulosin is a subtype-selective α 1A and α 1D adrenoceptor blocker. The former receptors predominate (≈ 70%) in the prostate gland, prostatic capsule, prostatic urethra and bladder.
Mechanism of action. Tamsulosin is a subtype-selective α1A and α1D adrenoceptor blocker.
Tamsulosin: an overview - PubMed
This article reviews the contemporary literature related to tamsulosin, which is now the most widely used alpha antagonist in treating benign prostatic hyperplasia.
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