Ciclosporin - Wikipedia
Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, eczema, and in …
Cyclosporine Uses, Side Effects & Warnings - Drugs.com
Cyclosporine is used to prevent organ rejection after a kidney, heart, or liver transplant. Cyclosporine is also used to treat severe psoriasis or severe rheumatoid arthritis. Cyclosporine may also be used for purposes not listed in this medication guide.
Cyclosporine (oral route) - Mayo Clinic
2024年2月1日 · Description. Cyclosporine is used in combination with other medicines (eg, azathioprine, steroid medicines) to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). It belongs to a group of medicines known as immunosuppressive agents.
Cyclosporin A (Cyclosporine A，环孢素) - 仅供科研 | 神经钙调蛋 …
Cyclosporin A (Cyclosporine A) 是一种免疫抑制剂，能与亲环素结合，抑制 protein phosphatase 2B (PP2B/calcineurin) 活性的IC50 值为 7 nM。 Cyclosporin A 也抑制 CD11a/CD18 粘附分子。
Cyclosporine: MedlinePlus Drug Information
Cyclosporine (modified) is also used alone or with methotrexate (Rheumatrex) to treat the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints) in patients whose symptoms were not relieved by methotrexate alone.
Cyclosporine: Uses, Interactions, Mechanism of Action - DrugBank …
Cyclosporin shows a linear clearance profile that ranges from 0.38 to 3 Lxh/kg 5, however, there is substantial inter- patient variability. 9 A 250 mg dose of cyclosporine in the oral soft gelatin capsule of a lipid micro-emulsion formulation shows an approximate clearance of 22.5 L/h. 14
环孢素 - 维基百科，自由的百科全书
环孢素 （英語： Cyclosporine、Cyclosporine A、Ciclosporin）也称为“ 环孢菌素 ”或“ 环孢霉素 ”，属一种 钙调磷酸酶 抑制剂，被廣泛用於預防 器官移植 排斥的 免疫抑制劑。. 它藉由抑制 T細胞 的活性跟生長而達到抑制 免疫系統 的活性。. 环孢素于1969年由 挪威 ...
Cyclosporine - StatPearls - NCBI Bookshelf
2023年8月28日 · Cyclosporine is an immunosuppressive agent used to treat organ rejection post-transplant. It also has use in certain other autoimmune diseases, treatment of organ rejection in kidney, liver, and heart allogeneic transplants, rheumatoid arthritis when the condition has not adequately responded to methotrexate.
Ciclosporin - Pharmaceutical Drugs - NCBI Bookshelf
Oral administration of immunosuppressive doses of ciclosporin reduced the trabecular bone volume of Sprague-Dawley rats. Osteoclast number and bone resorption were significantly increased at low (7.5 mg/kg bw per day) and high (15 mg/kg bw per day) doses of Ciclosporin (Movsowitz et al., 1988).
CICLOSPORIN - Pharmaceuticals - NCBI Bookshelf
Ciclosporin, a calcineurin inhibitor, is a potent immunosuppressant that is virtually non-myelotoxic but markedly nephrotoxic.