Intragenic Definition & Meaning - Merriam-Webster
The meaning of INTRAGENIC is being or occurring within a gene. How to use intragenic in a sentence.
What is the Difference Between Intragenic and Intergenic Suppressor ...
2019年4月18日 · The main difference between intragenic and intergenic suppressor mutation is that intragenic suppressor mutation occurs in the same gene as the original mutation whereas intergenic suppressor mutation occurs somewhere else in the genome.
Intragenic DNA inversions expand bacterial coding capacity
2024年9月25日 · Intragenic invertons allow a gene to encode two or more versions of a protein by flipping a DNA sequence within the coding region, thereby increasing coding capacity without increasing genome...
Intragenic DNA methylation prevents spurious transcription
2017年2月22日 · Intragenic DNA methylation, dependent on Dnmt3b, protects the gene body from spurious entry of RNA Polymerase II and aberrant transcription initiation events.
Suppressor Mutants: History and Today’s Applications
The two largest categories of suppressors, which specify where the secondary mutation occurs, are “intragenic” or “intergenic” suppressors (3). Intragenic suppression occurs when the original mutation and the suppressor mutation occur within the same gene (1, 3).
Intragenic DNA methylation: implications of this epigenetic mechanism ...
2011年12月13日 · This review will examine the evidence for the function of intragenic methylation in gene transcription, and discuss the significance of this in carcinogenesis and for the future use of therapies...
A Systematic Survey of an Intragenic Epistatic Landscape
2014年11月3日 · Using random mutagenesis, an assessment of more than 100,000 mutations (and 40,000 double mutants) in an RNA recognition motif in Saccharomyces cerevisiae yielded the largest and most systematic picture of intragenic epistasis to date (Melamed et al. 2013). Epistasis has also been studied in vivo.
Roles of Intragenic and Intergenic L1s in Mouse and Human
2014年11月19日 · The structure of mouse L1 is distinguished from human L1 by the presence of a 200 bp repeat in the 5′ UTR of the former. We found that mouse intragenic L1 has significantly higher repeat copy numbers than intergenic L1, suggesting that this is …
Whole genome sequencing facilitates intragenic variant interpretation ...
2021年11月13日 · Intragenic modifiers (in-phase, second-site variants) are known to have dramatic effects on clinical outcomes, affecting disease attributes such as severity or age of onset.
Intragenic Recombination - SpringerLink
2016年1月1日 · Intragenic recombination is a rare event that involves crossover between alleles of a locus. Learn how to test the order of mutant alleles and the role of intragenic recombination in preserving protein function.
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