Letrozole (Femara) | Cancer information | Cancer Research UK
Letrozole lowers the levels of the female sex hormone oestrogen in the body. Oestrogen stimulates some breast cancers to grow. These breast cancers are called hormone sensitive or hormone receptor positive. Letrozole can stop or slow the growth of these cancers. Letrozole only works in women who have had their menopause.
Hormone therapy for breast cancer - Cancer Research UK
Hormones can stimulate some breast cancer cells to grow. Hormone therapy works by either lowering the amount of hormones in the body or by blocking them from getting to breast cancer cells. Hormone therapy is also known as endocrine therapy. There are a number of different types of hormone therapy. The type you need depends on a number of factors.
A trial looking at letrozole after hormone therapy for early breast ...
2018年1月29日 · And research had shown that having letrozole for another 5 years, after the first 5 years of hormone therapy, may further reduce the risk of the cancer coming back. The results of a small study had shown that having intermittent letrozole may be as good as, or even better than, having it continuously.
A trial of megestrol acetate and letrozole for ... - Cancer Research UK
letrozole and a low dose of megestrol acetate (treatment B) letrozole and a high dose of megestrol acetate (treatment C) After finishing hormone treatment, everyone has surgery to remove the breast cancer. The main aim of this trial is to find out if megestrol acetate and letrozole is better than letrozole alone before surgery for breast cancer.
A trial of camizestrant for breast cancer (SERENA 6)
2024年7月15日 · In step 1 everyone takes letrozole or anastrozole with either abemaciclib, palbociclib or ribociclib. You give a blood sample every 8 to 12 weeks. The team use the blood samples to look for the gene change (mutation) in ESR1. They do this by looking for small pieces of the cancer DNA (ctDNA) in the blood.
A study looking at why some breast cancers respond better than …
2016年11月21日 · 89 women who were taking letrozole took part in this study. Before starting letrozole, the women had a sample of their breast cancer tissue (a biopsy) taken. They had another biopsy 2 weeks and 3 months after starting treatment. Researchers looked at the changes in the genes of the cancer tissue. They identified changes in 4 genes.
Targeted and immunotherapy drugs for breast cancer
an aromatase inhibitor ( such as anastrozole, exemestane or letrozole) fulvestrant; This treatment is usually for people whose breast cancer has spread to lymph nodes in the armpit and has a high risk of coming back (recurrence). Your breast cancer must also be hormone receptor positive and HER2 negative.
Hormone therapy for womb cancer - Cancer Research UK
The most common hormone therapy for womb cancer that has come back or that is advanced is progesterone. Types of progesterone include: medroxyprogesterone acetate (Provera) megestrol acetate (Megace) Other hormone therapies that are sometimes used to treat womb cancer include: tamoxifen. letrozole.
Hormone therapy for women | Sexuality and cancer - Cancer …
2024年9月30日 · Some post menopausal women with breast cancer take aromatase inhibitors instead of tamoxifen. Examples of aromatase inhibitors include anastrozole (Arimidex) or letrozole (Femara). These medicines also lower levels of oestrogen, which can reduce sexual desire. Aromatase inhibitors may have side effects such as fatigue and depression.
A trial looking at palbociclib and letrozole before breast cancer ...
103 had letrozole on its own; 68 had letrozole for 2 weeks followed by letrozole and palbociclib for the next 12 weeks; 69 had palbociclib for 2 weeks followed by letrozole and palbociclib for the next 12 weeks; 67 letrozole and palbociclib for 14 weeks; For every 3 women in group A, there were 2 women in group B, group C or group D.