List of Macrolides - Drugs.com
Macrolides are a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria. Macrolides inhibit protein synthesis in bacteria by reversibly binding to the P site of the 50S unit of the ribosome.
Macrolide - Wikipedia
Macrolide. Erythromycin. The macrolide ring is the lactone (cyclic ester) at upper left. Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered.
Macrolides: Drug Class, Uses, Side Effects, Drug Names - RxList
Macrolides are antibiotics used for infections caused by gram-positive bacteria (streptococcal and pneumococcal infections). Learn about how they work, usages, side effects, and a list of drugs.
Macrolides - StatPearls - NCBI Bookshelf
2020年2月1日 · Macrolides are a class of drugs used to manage and treat various bacterial infections. Azithromycin, clarithromycin, and erythromycin are commonly used to treat infections like pneumonia, sinusitis, pharyngitis, and tonsillitis. They are also used in uncomplicated skin infections and otitis media in pediatric patients.
Macrolides: From Toxins to Therapeutics - PMC
Macrolide toxins originating from marine and microbial sources represent a vast library of chemical structures with varying mechanisms of toxicity. Marine macrolide toxins are of particular interest, as the number of known toxins has increased greatly over the past 50 years.
Macrolides: Uses, common brands, and safety info - SingleCare
2022年3月26日 · Macrolides are a type of broad-spectrum antimicrobial used to fight against various bacteria such as mycoplasma, chlamydia, and legionella. They are most effective against gram-positive cocci bacteria and treat infections of the lung, skin, and soft tissues.
Macrolides - Macrolides - Merck Manual Consumer Version
Macrolides are a class of antibiotics that are often used to treat infections in people who are allergic to penicillins. Macrolides include the following: Azithromycin. Clarithromycin. Erythromycin. Fidaxomicin.
How macrolide antibiotics work - PMC - PubMed Central (PMC)
Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome. They bind at the nascent peptide exit tunnel and partially occlude it. Thus, macrolides have been viewed as ‘tunnel plugs’ that stop synthesis of every protein.
Macrolides - Macrolides - MSD Manual Consumer Version
Macrolides. By Brian J. Werth, PharmD, University of Washington School of Pharmacy. Reviewed/Revised May 2024. Macrolides are a class of antibiotics that are often used to treat infections in people who are allergic to penicillins.
Macrolides - Macrolides - MSD Manual Professional Edition
Macrolides. By Brian J. Werth, PharmD, University of Washington School of Pharmacy. Reviewed/Revised May 2024. Macrolides are antibiotics that are primarily bacteriostatic; by binding to the 50S subunit of the ribosome, they inhibit bacterial protein synthesis.