Nephrotoxicity - Wikipedia
Nephrotoxicity is the poisonous effect of some substances on kidney function. Learn about the different forms of nephrotoxicity, the drugs and chemicals that cause it, and how it is monitored and diagnosed.
Nephrotoxic Medications - StatPearls - NCBI Bookshelf
2023年6月21日 · Numerous drugs used to manage and treat multiple diseases, including hypertension, diabetes, and other pathologies, are nephrotoxic. These agents are in various classes and categories of medication. This activity reviews the indications, action, and contraindications for nephrotoxic drugs as a valuable agent in choosing key treatment strategies.
Drug-Induced Nephrotoxicity | AAFP
2008年9月15日 · Learn how drugs can cause acute or chronic kidney injury by different pathogenic mechanisms and how to prevent or minimize nephrotoxicity. Find out the risk factors, clinical recommendations, and...
The 6R’s of drug induced nephrotoxicity - BMC Nephrology
2017年4月3日 · This review article proposes a 6R approach to identify and manage drug induced kidney injury: risk, recognition, response, renal support, rehabilitation and research. It also discusses the epidemiology, mechanisms, risk factors …
Learn how drugs can injure the kidneys by different mechanisms and cause various renal syndromes. Find out the risk factors, clinical features, and strategies to prevent and treat drug-induced nephrotoxicity.
The Mechanism of Drug Nephrotoxicity and the Methods for …
Drug-induced nephrotoxicity develops according to one of the three mechanisms: (1) proximal tubular injury and acute tubular necrosis (ATN) (a dose-dependent mechanism), where the cause is related to apical contact with drugs or their metabolites, the transport of drugs and their metabolites from the apical surface, and the secretion of drugs fr...
Drug-induced nephrotoxicity - PubMed
2020年1月13日 · Nephrotoxicity can be defined as any renal injury caused directly or indirectly by medications, with acute renal failure, tubulopathies, and glomerulopathies as common clinical presentations.
Nephrotoxicity and Renal Pathophysiology: A ... - Oxford Academic
2018年6月25日 · This article reviews the causes, mechanisms and consequences of nephrotoxicity, the adverse effect of substances on renal function. It also discusses the similarities and differences between nephrotoxicity and renal pathology, the diagnosis and treatment of …
Drug-Induced Nephrotoxicity and Its Biomarkers - PMC
Nephrotoxicity is a kidney-specific feature in which excretion does not go smoothly owing to toxic chemicals or drugs (Finn and Porter, 2003; Galley, 2000). Approximately 20% of nephrotoxocity is induced by drugs, but medication of the elderly increases the incidence of nephrotoxicity up to 66% as the average life span increases.
Nephrotoxins and nephrotoxic acute kidney injury
2019年10月24日 · A review of nephrotoxic mechanisms, categories, and epidemiology, as well as prevention and monitoring strategies. Nephrotoxins are agents that can cause renal injury by vasoconstriction, tubular toxicity, or oxidative stress.