Nicotinic acetylcholine receptor - Wikipedia
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of many organisms.
烟酸 - 维基百科，自由的百科全书
烟酸 （英語： niacin 、 nicotinic acid，也称 維他命B3 、 維他命PP），分子式： C 6 H 5 N O 2，耐热，能升华。 首次描述於Hugo Weidel於1873年對 尼古丁 的研究。 它是人体必需的13种 维生素 之一，是一种水溶性维生素，属于 维生素B 族。 烟酸在人体内转化为 烟酰胺，烟酰胺是 辅酶Ⅰ 和 辅酶Ⅱ 的组成部分，参与体内 脂质 代谢，组织 呼吸 的 氧化 过程和 糖类 无氧分解的过程。 功能. 生理上為傳遞搬運電子，使末稍血管舒張作用。 具糖解作用，組織呼吸，脂肪合成。 （ …
Niacin - Wikipedia
Niacin is both a vitamin, i.e., an essential nutrient, marketed as a dietary supplement, and in the US, a prescription medicine. As a vitamin, it is precursor of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP).
Nicotine - Wikipedia
Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) [9] and is widely used recreationally as a stimulant and anxiolytic.
烟酸（niacin）名称由来与氧化还原辅酶 - 知乎 - 知乎专栏
烟酸原来的英文名称是nicotinic acid，中文音译为尼克酸，意译为烟酸或烟碱酸，如果直译的话，就是尼古丁酸。. 这是因为，烟酸最初是从尼古丁得到的。. 1873年，化学家Hugo Weidel在研究尼古丁的时候，用硝酸氧化尼古丁得到了烟酸。. 其实，烟酸与尼古丁在化学 ...
Nicotinic receptors: allosteric transitions and therapeutic targets …
Nicotinic receptors — a family of ligand-gated ion channels that mediate the effects of the neurotransmitter acetylcholine — are among the most well understood allosteric membrane proteins...
Nicotinic Acetylcholine Receptors and Nicotine Addiction: A Brief ...
Nicotine is a highly addictive drug found in tobacco that drives its continued use despite the harmful consequences. The initiation of nicotine abuse involves the mesolimbic dopamine system, which contributes to the rewarding sensory stimuli and associative learning processes in the beginning stages of addiction.
Understanding of nicotinic acetylcholine receptors | Acta ...
2009年6月5日 · Nicotine exerts its biological effects through nicotinic acetylcholine receptors (nAChRs). nAChRs are prototypical members of the ligand-gated ion channel superfamily of neurotransmitter...
尼古丁 - 维基百科，自由的百科全书
2024年7月29日 · 尼古丁 （英语： Nicotine），俗称 烟碱，是一种发现于 茄科 植物 的强效拟 副交感神经 生物碱，是 香烟 的主要化学成分和主要致瘾成分，属于 兴奋剂 的一种。. 尼古丁是一种 烟碱型乙酰胆碱受体 激动剂， [3][4] 而在 nAChRα9 和 nAChRα10 上作为 受体拮抗剂。. [3 ...
Nicotinic acetylcholine receptor redux: Discovery of ... - Science
2021年8月13日 · Nicotinic AChRs were the first ion channels to be isolated. Recent studies have identified molecules that control nAChR biogenesis, trafficking, and function. These nAChR accessories include protein and chemical chaperones as well as auxiliary subunits.