Perphenazine - Wikipedia
Perphenazine is a typical antipsychotic drug. Chemically, it is classified as a piperazinyl phenothiazine. Originally marketed in the United States as Trilafon, it has been in clinical use for decades.
Perphenazine: MedlinePlus Drug Information
Perphenazine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Perphenazine is also used to control severe nausea and vomiting in adults. Perphenazine is in a class of medications called conventional antipsychotics.
Perphenazine: Uses, Interactions, Mechanism of Action
Perphenazine is a piperazinyl phenothiazine, acts on the central nervous system, and has a greater behavioral potency than other phenothiazine derivatives whose side chains do not contain a piperazine moiety. It is a member of a class of drugs called phenothiazines, which are dopamine D1/D2 receptor antagonists.
Perphenazine: Dosage, Mechanism/Onset of Action, Half-Life
Mechanism of Action. Perphenazine is a piperazine phenothiazine antipsychotic which blocks dopamine, subtype 2 (D 2), receptors in mesolimbocortical and nigrostriatal areas of the brain (APA [Lehman, 2004]).
Perphenazine: Package Insert / Prescribing Info - Drugs.com
Indications and Usage for Perphenazine. Perphenazine is indicated for use in the treatment of schizophrenia and for the control of severe nausea and vomiting in adults. Perphenazine has not been shown effective for the management of behavioral complications in …
Perphenazine for schizophrenia - PMC
Perphenazine is an old phenothiazine antipsychotic with a potency similar to haloperidol. It has been used for many years and is popular in the northern European countries and Japan. To examine the clinical effects and safety of perphenazine for ...
Perphenazine: Use, dosage, interactions & adverse effects
2023年11月10日 · Perphenazine is an antipsychotic medication used in the treatment of schizophrenia and other psychotic disorders. It belongs to a class of medications called first-generation or typical antipsychotic drugs, which should be taken as prescribed because they can cause severe adverse effects. [1] Brand names. Uses. Action. Dosage. Half-life.
Perphenazine Monograph for Professionals - Drugs.com
2012年11月6日 · Perphenazine (Monograph) Brand name: Trilafon. Drug class: Phenothiazines. VA class: CN701. Chemical name: 2- [4- [3- (2-chloro-10H-phenothiazin-10-yl) propyl]piperazin-1-yl]ethanol. Molecular formula: C 21 H 26 CIN 3 OS. CAS number: 58-39-9. Perphenazine is also contained as an ingredient in the following combinations:
Oral Perphenazine 8 mg: A Low-Cost, Efficacious Antiemetic Option
First, and principally, we endorse that oral perphenazine 8 mg (OP8) is a low-cost and efficacious tool for prevention of PONV.
DailyMed - PERPHENAZINE tablet, film coated
2010年8月18日 · Perphenazine is indicated for use in the treatment of schizophrenia and for the control of severe nausea and vomiting in adults. Perphenazine has not been shown effective for the management of ... CONTRAINDICATIONS.