3D bioprinted cancer models: from basic biology to drug …
2022年10月24日 · Advanced 3D bioprinted cancer models have the potential to revolutionize the way we discover therapeutic targets, develop new drugs and personalize...
3D bioprinting of tumor models and potential applications
4 天之前 · The development of 3D bioprinting of tumor models has been widely regarded as a significant advancement in medical research. By creating more realistic and reliable tumor models, researchers can better understand the biological characteristics, progressions, and treatment responses of tumors. This will help accelerate drug screening and ...
3D Bioprinting of Tumor Models for Cancer Research
2020年8月10日 · In this Review, we discussed the 3D bioprinted tumor models that integrate their microenvironment with different cell types, substrates, and bioprinting modalities and their application in drug screening and therapy.
3D Bioprinted cancer models: Revolutionizing personalized cancer ...
2021年4月1日 · 3D bioprinted constructs form physiologically relevant cell–cell and cell–matrix interactions. Bioprinted cancer models mimic the 3D heterogeneity of real tumors. After cardiovascular disease, cancer is the leading cause of death worldwide with devastating health and economic consequences, particularly in developing countries.
Advances in 3D bioprinting for the biofabrication of tumor models
2021年3月1日 · By incorporating factors like stromal cells, vasculature, hydrogels, and functional molecules into the bioprinting process, researchers are now able to create human tumor models that quite realistically represent human glioblastoma, breast, cervical, ovarian, hepatoma, lung, colon, and oral cancers.
3D bioprinted tumor model: a prompt and convenient platform …
2024年3月23日 · In terms of mimicking the TME, 3D bioprinting has been used to create an organized milieu for investigating the interplays between different cell types and a replicated model for tumor metastasis and angiogenesis [18].
3D bioprinting for reconstituting the cancer microenvironment
2020年7月27日 · In this review, we discuss the applications of 3D bioprinting in mimicking cancer microenvironment, their use in immunotherapy as prescreening tools, and overview of current bioprinted...
Recent advancements and challenges in 3D bioprinting for cancer ...
2024年11月1日 · By recapitulating tumor microenvironments and heterogeneity, 3D bioprinted models offer valuable platforms for studying cancer biology, drug responses, and personalized medicine.
3D bioprinted tumor model with extracellular matrix enhanced …
This study fabricate a reliable tumor model by 3D bioprinting of MCF-7 cells in vitro, which mimics the key biological characteristics of in vivo tumors including the complex ECM barriers, multicellular interaction and proliferative gradients. Also, the ECM remodeling and EMT of MCF-7 cells have been tracked under the condition of 3D culture.
Hybrid 3D microfluidic bioprinting for the engineering of cancer models ...
2024年11月4日 · Herein, the combination of 3D bioprinting with high-throughput dispensing using a custom microfluidic system and nanoclay-based inks is presented. This approach was found to enhance printability, retention, and controlled release of bioactive factors.
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