ADH4 Gene - GeneCards | ADH4 Protein | ADH4 Antibody
2024年12月9日 · ADH4 (Alcohol Dehydrogenase 4 (Class II), Pi Polypeptide) is a Protein Coding gene. Diseases associated with ADH4 include Alcohol Dependence and Cluster Headache. Among its related pathways are Oxidation by cytochrome P450 and Signaling by Retinoic Acid.
醇脱氢酶4 - 维基百科，自由的百科全书
醇脱氢酶4（英語： Alcohol dehydrogenase 4 ）是由人类基因 ADH4 编码的蛋白质 [1] 。 ADH4编码 醇脱氢酶 家族中的第II类醇脱氢酶4π亚基。 这一类脱氢酶可以催化许多底物，包括 乙醇 、 视黄醇 以及其它 脂肪醇 、 羟类固醇 （ 英语 ： hydroxysteroids ） 和 脂质过氧化 产物。
乙醇脱氢酶 - 百度百科
乙醇脱氢酶够以 烟酰胺腺嘌呤二核苷酸 (NAD)为辅酶,催化伯醇和醛之间的 可逆反应：CH3CH2OH+ NAD+→ CH3CHO +NADH+ H+。 在人和哺乳动物体内,乙醇脱氢酶与 乙醛脱氢酶 (ALDH)构成了乙醇脱氢酶系,参与体内乙醇代谢，是人和动物体内重要的 代谢酶。 作为生物体内主要 短链 醇代谢的 关键酶，它在很多生理过程中起着重要作用。 它是一种广泛 专一性 的含锌金属酶。 乙醇脱氢酶乙醇氧化体系是在肝脏中代谢酒精的一条主要途径。 乙醇脱氢酶氧化体系包 …
ADH4 - Wikipedia
It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
127 - Gene ResultADH4 alcohol dehydrogenase 4 (class II), pi ...
2024年8月27日 · This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
2023年11月23日 · This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide [Homo …
Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]
All-trans-retinol dehydrogenase [NAD (+)] ADH4 - DrugBank Online
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol (PubMed:17279314). Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate (PubMed:16081420).
Entry - *103740 - ALCOHOL DEHYDROGENASE 4; ADH4 - OMIM
The ADH4 gene encodes alcohol dehydrogenase 4, which belongs to class II of the ADH genes. ADH4 (pi) isozyme, characteristic of adult liver, was termed class II by Vallee and Bazzone (1983), who referred to ADH5 (chi; 103710) as class III.
ADH4 Gene Variation is Associated with Alcohol Dependence and …
2005年10月12日 · These findings suggest that ADH4 genotypes predispose to alcohol dependence and drug dependence in a recessive manner, a predisposition that is population specific. SNP2 or SNP6 was the marker...