Alpha amylase inhibitor - Wikipedia
In molecular biology, alpha-amylase inhibitor (or α-...) is a protein family which inhibits mammalian alpha-amylases specifically, by forming a tight stoichiometric 1:1 complex with alpha-amylase. This family of inhibitors has no action on plant and microbial alpha amylases.
Amylase Inhibitor - an overview | ScienceDirect Topics
Amylases catalyze the breakdown of starch into sugars, and are thus essential digestive enzymes of herbivorous species, including vertebrates and insects. Amaranth α-amylase inhibitor (AAI) is a 32-residue peptide that has been extensively studied by NMR, with solution structural studies revealing the presence of a cystine knot [145,146].
Amylase Inhibitors – Health Information Library - PeaceHealth
Amylase inhibitors are substances that reduce the activity of amylase, the digestive enzyme required to break down dietary starches into absorbable glucose. Many plants and plant foods, including vegetables and legumes, contain amylase-inhibiting compounds that may be useful in preventing and treating type 2 diabetes.
Alpha Amylase Inhibitor - an overview | ScienceDirect Topics
Alpha-glucosidase and alpha-amylase inhibitors help retard post-prandial blood glucose increase. Food compounds with such properties include tannins (ellagitannins and proanthocyanidins), anthocyanins, chlorogenic acid in coffee and many other polyphenols (Boath, Grussu, Stewart, & McDougall, 2012).
The Truth About Starch Blockers - WebMD
Amylase inhibitors, also called starch blockers, prevent starches from being absorbed by the body. When amylase is blocked, those carbs pass through the body undigested, so you don't absorb...
Bioactive α-Amylase Inhibitors: Sources, Mechanism of Action ...
Among all different enzyme inhibitors, α-amylase inhibitors (α-AIs) are prime and attractive candidates for studies and research due to their potential applications. α-AIs display a great diversity in their structure, expression, inhibition specificity, and effectiveness against digestive enzymes from several sources including mammalians ...
Amylase inhibitors and their biomedical applications
2013年3月18日 · Inhibition of α-amylase along with α-glucosidase can significantly reduce the post-prandial increase of blood glucose and can be an important strategy in the control of blood glucose level in the type-2 diabetic patients. Hence, pancreatic α-amylase and gastric glucoamylases are the major therapeutic targets for the type-2 diabetes mellitus.
Insights into the Inhibition Mechanism of Human Pancreatic α-Amylase…
Insights into the Inhibition Mechanism of Human Pancreatic α-Amylase, a Type 2 Diabetes Target, by Dehydrodieugenol B Isolated from Ocimum tenuiflorum - PMC. As a library, NLM provides access to scientific literature.
The inhibitory mechanism of amylase inhibitors and research
Several classes of phytochemicals, including polyphenols and flavonoids, have been shown to inhibit amylase, including certain types of food-grade nanoparticles. In this review, we summarize the main functions and characteristics of amylases within the human body, as well as their interactions with amylase inhibitors.
Natural Inhibitors of Mammalian α-Amylases as Promising …
2023年11月20日 · α-Amylase is a generally acknowledged molecular target of a distinct class of antidiabetic drugs named α-glucosidase inhibitors. This class of medications is scarce and rather underutilized, and treatment with current commercial drugs …
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