The BHMT-betaine methylation pathway epigenetically modulates ...
2021年5月11日 · BHMT is an enzyme that catalyzes the remethylation of homocysteine (Hcy) to methionine with betaine as the methyl donor. Methionine is then converted to SAM, the key methyl donor required for histone and DNA methylation (Fig 1). When MTR activity is downregulated, levels of SAM are also decreased.
Betaine—homocysteine S-methyltransferase - Wikipedia
In the field of enzymology, a betaine-homocysteine S-methyltransferase also known as betaine-homocysteine methyltransferase (BHMT) is a zinc metallo-enzyme that catalyzes the transfer of a methyl group from trimethylglycine and a hydrogen ion from homocysteine to produce dimethylglycine and methionine respectively: [2]
The state of the art in scale inhibitor squeeze treatment
2020年8月19日 · Lots of research efforts have been focused on improving squeeze efficiency through (1) enhancing scale inhibitor retention (adsorption or precipitation), (2) optimizing the delivery of scale inhibitors to the target zone, and (3) improving monitoring methods.
Deficiency of betaine-homocysteine methyltransferase activates …
Betaine-homocysteine methyltransferase (BHMT) regulates protein methylation and is correlated with tumorigenesis; however, the effects and regulation of BHMT in hepatocarcinogenesis remain largely unexplored. Here, we determined the clinical significance of BHMT in the occurrence and progression of hepatocellular carcinoma (HCC) using tissue ...
甜菜碱高半胱氨酸甲基转移酶（BHMT）依赖的人类健康和肿瘤肝 …
甜菜碱高半胱氨酸甲基转移酶（BHMT）依赖的人类健康和肿瘤肝脏中的甲基化途径。. 致癌作用是一个多步骤，多因素的过程。. 它包括密切相关的遗传，表观遗传，营养和环境因素。. 人肝细胞癌（HCC）是最常见和致命的癌症之一。. S-腺苷甲硫氨酸（SAM）浓度 ...
Betaine-homocysteine methyltransferase: Human liver …
2011年2月1日 · BHMT catalyzes the transfer of a methyl group from betaine to homocysteine, resulting in the generation of dimethylglycine and methionine. Homocysteine remethylation is a critical step in the synthesis of S-adenosylmethionine (AdoMet), the methyl donor for most methylation reactions [3].
Bhmt/Water Treatment Chemicals - Bhmtpmpa and Water …
BHMT is a scale and corrosion inhibitor used to cool circulating water units and boilers. Metal chelating agents and colour fixing agents for printing and textiles; Electronic plate complexing agent and metal scale cleaning agent.
Bis Hexamethylene Triamine (BHMT) Phosphonate - IRO …
Bishexamethylene triamine (BHMT) phosphonate is a high-efficient chelating scale inhibitor. It has a good effect on the carbonate and sulfate scale. BHMT phosphonate has good water-soluble properties and heat tolerance. It has high calcium ion tolerance in wide pH ranges and temperatures as high as 120℃.
The Molecular and Cellular Effect of Homocysteine Metabolism …
2016年10月20日 · BHMT-dependent remethylation of Hcy occurs primarily in liver, kidney and lens, whereas the folate/vitamin B12-dependent route is found universally in all tissues. For folate-independent methionine remethylation, the regulation and/or expression of BHMT has been shown to affect Hcy concentrations in plasma with the wide clinical manifestations.
Association between BHMT and CBS gene promoter methylation …
2019年9月27日 · Abnormal methylation levels of BHMT and CBS are positively associated with Hcy levels. The present study is performed to explore the association between the methylation levels in the promoter...