Plaquenil Toxicity: How to Avoid this Bullseye - Review of Optometry
网页2021年12月15日 · Plaquenil Toxicity: How to Avoid this Bullseye. Learn the clinical indicators, risk factors and screening guidelines to properly monitor for this irreversible, rare condition in patients on this drug. By Luanne Chubb, OD. Plaquenil (hydroxychloroquine) is a disease-modifying anti-rheumatic drug used to treat patients with various inflammatory ...
Hydroxychloroquine Toxicity - EyeWiki
网页The early signs of hydroxychloroquine toxicity are macular edema and/or bilateral granular depigmentation of the RPE in the macula. With continued exposure to the drug, this can progress to an atrophic bullseye maculopathy with concentric rings of hypopigmentation and hyperpigmentation surrounding the fovea [3] [4].
Hydroxychloroquine-Induced Retinal Toxicity - American Academy …
网页2011年6月1日 · On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful.
Recommendations on Screening for Chloroquine and …
网页The clinical picture of HCQ and CQ toxicity had been characterized classically as a bilateral bull’s-eye maculopathy, an appearance caused by a ring of parafoveal RPE depigmentation that spares a foveal island.
Imaging in Hydroxychloroquine Toxicity - Retina Today
网页Fundus photography of the right (A) and left eye (B) in a patient with early hydroxychloroquine toxicity is shown. A parafoveal early bulls-eye maculopathy is evident in both eyes.
Multimodal Imaging in Plaquenil Toxicity - Review of Ophthalmology
网页2014年8月6日 · Figure 1. Fundus photos (top) demonstrate extensive paracentral depigmentation of the retinal pigment epithelium sparing the central fovea bilaterally, consistent with bull’s-eye maculopathy. Fluorescein angiography (bottom) shows parafoveal granular hyperfluorescence correlating to …
Hydroxychloroquine retinal toxicity: The bull's eye in the human eye
网页2020年6月25日 · Bull's eye maculopathy could be detected in Stargardt's disease, Bardet-Biedl syndrome, Leber's congenital amaurosis, and cone dystrophy. Central retinal artery occlusion, commotion retinae and macular hole could cause cherry-red spot over the central macula, but not Bull's eye maculopathy.
Hydroxychloroquine-induced Retinal Toxicity - National Center for ...
网页2023年5月30日 · Hydroxychloroquine retinopathy was previously considered rare since it was typically diagnosed at an advanced stage with symptoms of central visual loss and visible fundoscopic changes, such as “bull’s eye” maculopathy, characterized by loss of retinal pigment epithelium.
Bull's Eye Maculopathy: Signs, Causes, Diagnosis and More
网页2024年6月8日 · Bull’s-eye maculopathy is a term used to describe the appearance of a target's bull's-eye ring on a damaged retina, an essential part of the eye that helps with sight. This damage can be caused by different eye conditions or long-term use of certain drugs that suppress the immune system.
Bull’s Eye Maculopathy - Cleveland Clinic
网页2023年7月23日 · What is bull’s eye maculopathy? Bull’s eye maculopathy is a rare condition that causes degeneration (deterioration) of your macula. The macula is part of your retina, which is the layer of tissue at the back of your eye. The degeneration appears as discolored rings on your macula, like a target or bull’s eye pattern.