Evidence-Based Management of Oral Mucositis | JCO Oncology …
WEBFeb 3, 2020 · The SWISH trial demonstrated that prophylactic use of dexamethasone mouthwash significantly reduces the incidence and severity of stomatitis in patients receiving the mTOR inhibitor everolimus for breast cancer (compared with historical control patients). 11 Topical, intralesional, or systemic steroids are currently used for the management of ...
Dexamethasone 1mg/mL Mouthwash - SingHealth
WEBOct 31, 2018 · Dexamethasone mouthwash can be used to prevent swollen mouth ulcers. This medication can be taken by cancer patients. Learn about its uses, dosage, side effects, precautions, contraindications, handling and storage.
Dexamethasone Oral Solution: Uses & Side Effects - Cleveland Clinic
WEBDexamethasone oral solution is a corticosteroid medication that treats inflammation of the skin, joints, lungs and other organs. It may be prescribed for conditions like asthma, allergies and arthritis. It can also treat blood disorders and …
SWISH Four Times a Day to Keep Oral Mucositis Away - Medscape
WEBMar 28, 2017 · Results show that during a period of 8 weeks, the dexamethasone mouthwash reduced the proportion of all-grade stomatitis by 61% and reduced grade 2 or worse stomatitis by 91% when compared with...
Dexamethasone Mouth Rinse Should Be Routine Part of …
WEBOct 25, 2016 · Dexamethasone mouth rinse should be given prophylactically to prevent stomatitis associated with everolimus (Afinitor)/exemestane in metastatic breast cancer, according to Hope S. Rugo, MD, principal investigator of the SWISH trial and Director of Breast Oncology and Clinical Trials Education at the University of …
Efficacy and safety of dexamethasone-based mouthwash to …
WEBJun 2, 2022 · Therefore, this study aimed to assess the efficacy and safety of a dexamethasone-based mouthwash for preventing chemotherapy-induced stomatitis in patients with early breast cancer. Methods: We conducted a multicenter, randomized, controlled phase II trial.
EFFICACY AND SAFETY OF A DEXAMETHASONE-BASED MOUTHWASH …
WEBThe dexamethasone-based mouthwash safely reduced stomatitis incidence and severity in patients receiving chemotherapy for early breast cancer. Phase 3 clinical trials are warranted for validating our results.
Study protocol for efficacy and safety of steroid-containing mouthwash …
WEBFeb 13, 2020 · The current randomised, controlled, phase 2 trial aims to assess the safety and efficacy of a dexamethasone-based elixir mouthwash for preventing chemotherapy-induced stomatitis in patients with early breast cancer.
Effectiveness and safety of a novel dexamethasone mouthwash …
WEBNov 14, 2020 · Objective: To present a new dexamethasone mouthwash formulation and analyze its effectiveness and safety among patients receiving stomatitis-producing antineoplastic agents. Method: Prospective observational study conducted in a university hospital between March 2017 and November 2019.
SWISH-ing steroids: new standard of care to prevent ... - The Lancet
WEBMar 14, 2017 · Should the prophylactic use of dexamethasone mouthwash four times daily be a new standard of care for everolimus-induced oral mucositis? The reduction in stomatotoxic effect in the SWISH trial compared with BOLERO-2 is certainly impressive.