Ethambutol: Uses, Interactions, Mechanism of Action - DrugBank …
网页Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. 13 Ethambutol was first described in the literature in 1961. 11 It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. 11
Ethambutol - StatPearls - NCBI Bookshelf
网页2024年5月2日 · Ethambutol is a bacteriostatic drug that inhibits cell wall synthesis and is used to manage and treat tuberculosis (TB). The mechanism of action, dosing considerations, pharmacokinetics, adverse event profiles, contraindications, boxed warnings, and monitoring strategies are highlighted within a multi-drug treatment.
Ethambutol: An overview - UpToDate
网页2024年4月25日 · Ethambutol is an antimycobacterial agent that is most commonly used in combination with other drugs in the treatment of tuberculosis . It is also used as part of a combination regimen in the therapy of nontuberculous mycobacterial infections .
Ethambutol - Wikipedia
网页Ethambutol (EMB, E) is a medication primarily used to treat tuberculosis. [4] It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. [5] It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii. [4] It is taken by mouth.
Comprehensive review on mechanism of action, resistance and …
网页2021年6月1日 · The current regimen for treating drug susceptible TB patients is a regimen consisting of an intensive phase of 2 months of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) followed by a continuation phase of 4 …
Ethambutol: Dosage, Mechanism/Onset of Action, Half-Life
网页2021年2月17日 · Mycobacterium avium complex (MAC) disease (off-label use): Oral: Nodular/bronchiectatic disease: 25 mg/kg 3 times weekly in combination with a 3-times-weekly regimen of a macrolide (azithromycin or clarithromycin) and rifampin; continue treatment until patient is culture negative on therapy for 1 year.
Ethambutol - PubMed
网页2024年5月2日 · Ethambutol is a bacteriostatic drug that inhibits cell wall synthesis and is used to manage and treat tuberculosis (TB). The mechanism of action, dosing considerations, pharmacokinetics, adverse event profiles, contraindications, boxed warnings, and monitoring strategies are highlighted within a mul ….
Determining the Mechanism of Action of Ethambutol - NEJM …
网页2020年5月8日 · Ethambutol is one of the backbone agents for the management of Mycobacterium tuberculosis (Mtb) infections and of other pathogenic mycobacterial species. Its antimicrobial effect is known to be related to interaction with three membrane-embedded arabinosyltransferases — EmbA, EmbB, and EmbC — involved in the synthesis of the mycobacterial ...
网页Ethambutol (Emb) DRUG CLASS: UNSPECIFIED Activity against TB, mechanism of action, and metabolism Bacteriostatic; inhibitor of cell wall synthesis; bactericidal only at the high end of the dosing range. At doses used over long periods of time, ethambutol protects against further development of resistance. Dose Adults: 15–25 mg/kg/day. Higher ...
Ethambutol | C10H24N2O2 | CID 14052 - PubChem
网页Ethambutol is an ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria.
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