Rapid Crystal Dissolution in Gout - Medscape
For example, most patients (90%) with <10 years duration of gout but few patients (25%) with >10 years gout duration, were free of crystals by 12 months (median serum urate levels while on urate ...
Dual-energy CT: A New Diagnostic Tool for Gout - Medscape
Uric acid crystals were identified in synovial fluid in 12 patients, and CT was positive in all of them (100% sensitivity). In the 19 patients whose fluid was negative for uric acid crystals, CT ...
Treat Gout to Target Based on Uric Acid Level, Not Symptoms
2024年6月18日 · She argued that this controlled trial fills an evidence gap. T2T is defined as maintaining a serum uric acid (sUA) level below the physiologic threshold level of 36 mmol/L (< 6 mg/dL). T2S, in ...
Another Benefit of Gout Treatment: CV Risk Reduction - Medscape
May 16, 2024. 0. NEW YORK CITY — Urate, the culprit of gout, affects the vasculature in multiple ways that can raise cardiovascular risk (CV) in an individual with gout, and following guidelines ...
New Gout Drugs Might Increase Patients at Target Urate Level
2024年7月9日 · The proportion of patients achieving the more rigorous target of < 0.5 mg/dL was also higher with the higher and lower doses of ruzinurad vs placebo (43.1% and 38.8% vs 9.8%, respectively). The ...
Metformin Initiation Cuts Gout Risk in Prediabetes - Medscape
2024年5月30日 · Initiation vs no initiation of metformin resulted in 2.4 fewer cases of gout per 1000 person-years and a 32% reduced relative risk for incident gout (hazard ratio, 0.68; 95% CI, 0.48-0.96).
DECT Useful in Suspected Gout With Negative Joint Aspiration
2011年11月10日 · In part 1, investigators enrolled 40 patients with confirmed gout on the basis of the presence of crystals in their joint aspiration fluid and 40 patients with other joint disease and negative ...
Evaluating Knee Pain: The Latest in Diagnosis and Management
Synovial fluid shows 22,000 nucleated cells/μL (87% neutrophils) and negatively birefringent intracellular crystals that are consistent with gout; Gram stain and culture were negative. Plain ...
Treatment With Rasburicase of a Tophaceous Gout - Page 2
Gout is related to the deposition of MSU monohydrate crystals within the joints. It is the most common inflammatory joint disease in men, affecting at least 1% of the Western population.
New Gout Guidelines: Primary Care Pointers - Medscape
2021年3月2日 · It's recommended to start with low-dose allopurinol to reduce the likelihood of a hypersensitivity reaction or gout flare. Begin with 100 mg daily for most patients, which in most people will ...