Gout - Wikipedia
网页Gout (/ ɡ aʊ t / GOWT [9]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [4] [10] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [11] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [7]
A concise history of gout and hyperuricemia and their treatment
网页2006年4月12日 — First identified by the Egyptians in 2640 BC, podagra (acute gout occurring in the first metatarsophalangeal joint) was later recognized by Hippocrates in the fifth century BC, who referred to it as 'the unwalkable disease'.
Gout : Introduction to Gout - Johns Hopkins Arthritis Center
网页Perhaps the oldest known type of arthritis, gout or gouty arthritis, has a long and colorful history with some of the earliest descriptions dating back as far as the 5 th century B.C. Historically, gout as been called “the disease of kings” due to its association with rich foods and alcohol consumption.
Gout: An old disease in new perspective – A review - PMC
网页2017年5月10日 — Gout distinguished itself in the history of Homo sapiens since time immemorial. It appeared in medical records very early in the history of medical writing, and was also mentioned in the biographies of many famous names. It was depicted as the fate of a life of affluence as much as the challenge to a physician’s skill, and truly it was.
A brief history of gout - PubMed
网页Gout is relatively unique among rheumatological diseases in that its effects were common and, at least in history, disproportionately represented in prominent authority figures. Effective treatments have only been available for just over a century and therefore for the most part, the disease has run ….
Gout - StatPearls - NCBI Bookshelf
网页2019年11月30日 — Gout, once known as the "disease of kings and king of diseases," is among the most prevalent etiologies of chronic inflammatory arthritis in the United States, characterized by monosodium urate (MSU) monohydrate crystals deposition within tissues.[1][2] Hippocrates first described gout in ancient Greece; hence, it is the most understood and ...
A concise history of gout and hyperuricemia and their treatment
网页2006年4月12日 — With a history spanning more than 2500 years, gout is among the oldest recognized diseases. Its profound impact on patient quality of life, as illustrated in memorable medical cartoons and images (Figs (Figs1 1 and and2), 2), has even influenced historical events (see Historical asides, above).
Gout and Hyperuricemia: an Historical Perspective
网页2015年4月19日 — The discovery of the role of uric acid in the pathophysiology of gout has its own parallel history, a story that begins with Antoni van Leeuwenhoek of Delft (1632–1723). A Dutch biologist and father of microscopy, van Leeuwenhoek, was the first to observe capillaries, red blood cells, bacteria, protozoa, and spermatozoa accomplishments all ...
A brief history of gout - BHATTACHARJEE - Wiley Online Library
网页2009年3月28日 — Gout is relatively unique among rheumatological diseases in that its effects were common and, at least in history, disproportionately represented in prominent authority figures. Effective treatments have only been available for just over a century and therefore for the most part, the disease has run relatively unchecked.
Gout: A Disease of Kings - PubMed
网页First described as far back as 2640 B.C., gout is still the most common form of inflammatory arthritis haunting humans in the 21st century. The disease is caused by the chronic elevation of serum uric acid levels above the saturation point for monosodium urate crystal formation.