Graves’ disease - Nature Reviews Disease Primers
2020年7月2日 · Graves’ disease (GD), also known as von Basedow disease, is a syndrome characterized by an enlarged and overactive thyroid gland (Graves’ hyperthyroidism), ocular abnormalities (Graves’...
Graves Disease - StatPearls - NCBI Bookshelf
2023年6月20日 · Graves' disease is the most common cause of hyperthyroidism. It is a disorder with systemic manifestations that primarily affect heart, skeletal muscle, eyes, skin, bone, and liver. Failure to diagnose Graves' disease in a timely manner can predispose thyroid storm which carries high morbidity and mortality.
Graves’ Disease | New England Journal of Medicine
2016年10月20日 · Graves’ disease is the most common cause of hyperthyroidism, with an annual incidence of 20 to 50 cases per 100,000 persons. 10 The incidence peaks between 30 and 50 years of age, but...
Management of Graves Disease : A Review - JAMA Network
Thirteen randomized clinical trials, 5 systematic reviews and meta-analyses, and 52 observational studies were included in this review. Patients with Graves disease may be treated with antithyroid drugs, radioactive iodine (RAI), or surgery (near-total thyroidectomy).
Graves disease: latest understanding of pathogenesis and
2024年7月22日 · Graves disease is an autoimmune disease characterized by an enlarged and overactive thyroid gland 1. The main mechanism responsible for Graves hyperthyroidism is the activation of the...
Graves’ Disease and the Manifestations of Thyrotoxicosis
2024年9月24日 · Graves' disease (GD) is an autoimmune disorder characterized by hyperthyroidism and various systemic manifestations, including thyroid eye disease (TED) and, less commonly, dermopathy. This chapter provides an in-depth review of GD, covering its history, epidemiology, risk factors, and the molecular mechanisms underlying autoimmune hyperthyroidism.
Graves’ disease: moving forwards - PMC - PubMed Central (PMC)
Graves’ disease (GD) is an autoimmune disorder that develops because thyroid receptor autoantibodies (TRAbs) stimulate the thyroid-stimulating hormone (TSH) receptor (TSHR) on the thyroid gland. The interaction between antibody and receptor results in excessive thyroid hormone secretion (hyperthyroidism).
Management of Graves Disease: A Review - PubMed
2015年12月15日 · Management of Graves disease includes treatment with antithyroid drugs, RAI, or thyroidectomy. The optimal approach depends on patient preference and specific patient clinical features such as age, history of arrhythmia or ischemic heart disease, size of goiter, and severity of thyrotoxicosis.
This Review aims to provide an overview of the epidemiology, pathogenesis, and conventional treatment of Graves hyperthyroid-ism and Graves orbitopathy as well as a discussion of the most...
Graves' disease - PubMed
2020年7月2日 · Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is the most common cause of hyperthyroidism and occurs at all ages but especially in women of reproductive age.